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Postdoctoral Associate

**Required Qualifications** : (as evidenced by an attached resume)

Doctoral Degree (or foreign equivalent) in Biochemistry, Pharmacology, or a closely related field in hand by December 30, 2025.

Two or more years of research experience in the following areas

• Drug development.

• Pharmacokinetics and Pharmacodynamics.

• Protein structure analysis.

**Preferred Qualifications** :

Two or more years of research experience in the following areas:

• Enzymatic kinetics.

• Membrane-protein expression and purification.

• Proteomics.

• Drug efficacy and toxicity testing.

**Description of Duties** :

The Postdoctoral Associate will work on an NIH-funded project focusing on the roles of alkaline ceramidase 2 (ACER2) in chemotherapy-induced cancer metastasis and chemoresistance in Dr Cungui Mao’s laboratory in the department of Medicine and Cancer Center at Stony Brook University. ACER2 is a member of the alkaline ceramidase (ACER) family, originally identified in humans by the Mao lab. The lab previously demonstrated that ACER2 mediates various cellular responses by regulating bioactive sphingolipids, such as ceramides, sphingosine, and sphingosine-1-phosphate. Recent findings from the lab indicate that ACER2 plays important roles in mediating chemotherapy-induced tumor metastasis and cancer chemoresistance. For more information about the groundbreaking research in the Mao lab (https://cancer.stonybrookmedicine.edu/CancerResearch/LipidLaboratory/Mao-staff) please visit the Lipid Cancer Laboratory (https://cancer.stonybrookmedicine.edu/CancerResearch/LipidLaboratory) .

• Develop small molecule inhibitors of ACER2 as potential cancer therapeutics using high throughput screening (HTS) and study the anti-cancer efficacy, toxicity, pharmacokinetic and pharmacodynamic properties of the ACER2 inhibitors.

• Collect and analyze data, including periodical/literature search and utilizing specialized skills in related fields to analyze the collected data.

• Participate/assist in manuscript writing for publication in scientific journals and/or presentations.

• Perform lab maintenance, including equipment maintenance and ordering of supplies as needed.

• Attend scientific conferences and meetings.

• Other duties as assigned.

Special Notes:

The Research Foundation of SUNY is a private educational corporation. Employment is subject to the Research Foundation policies and procedures, sponsor guidelines and the availability of funding. FLSA Exempt position, not eligible for the overtime provisions of the FLSA. Minimum salary threshold must be met to maintain FLSA exemption.

Visit The Office of Postdoctoral Affairs (https://www.stonybrook.edu/commcms/postdoc/) to learn more about our postdoctoral community.

Resume/CV and cover letter should be included with the online application.

_Stony Brook University is committed to excellence in diversity and the creation of an inclusive learning, and working environment. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, familial status, sexual orientation, gender identity or expression, age, disability, genetic information, veteran status and all other protected classes under federal or state laws._

If you need a disability-related accommodation, please call the university Office of Equity and Access (OEA) at (631) 632-6280 or visit OEA (https://www.stonybrook.edu/commcms/oea/) .

_In accordance with the Title II Crime Awareness and Security Act_ a _copy of our crime statistics can be viewed_ here (https://www.stonybrook.edu/police/) _._

Visit our WHY WORK HERE (https://www.stonybrook.edu/jobs/working-here/) page to learn about the **total rewards** we offer.

SUNY Research Foundation: A Great Place to Work. (https://www.stonybrook.edu/human-resources/total-rewards/\_postdocs/rf\_postdoctoral\_employees/)

The starting salary range (or hiring range) to be offered for this position is noted below, it represents SBU’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

**Job Number:** 2504611

**Official Job Title:** : Postdoctoral Associate

**Job Field** : Post Doctoral

**Primary Location** : US-NY-Stony Brook

**Department/Hiring Area:** : Cancer Center

**Schedule** : Full-time

**Shift** : Day Shift **Shift Hours:** : 9-5 :

**Posting Start Date** : Dec 23, 2025

**Posting End Date** : Jan 5, 2026, 11:59:00 PM

**Salary:** : $50,000-$65,000

**Appointment Type:** : Regular

**Salary Grade:** : E89

**SBU Area:** : The Research Foundation for The State University of New York at Stony Brook

**Req ID:** 2504611