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Organization Overview

Our research is aimed at the identification of molecular mechanisms that control development and dysfunction of the mammalian cerebellum. We have chosen to study the cerebellum because it is a complex and highly stereotyped structure in which major pattern formation and functional organization occur postnatally. During the past century,classical neuroanatomical studies have very precisely described the complex events that must occur for formation of this brain structure,providing what might be considered as the most detailed information available concerning the development of a given brain region. An extensive literature has documented the importance of cell-cell interactions in the development and maintenance of normal cerebellar architecture,although the mechanisms mediating these interactions remain unknown. Identification of these mechanisms,and analysis of their functions throughout the central nervous system (CNS),are major priorities of the Heintz laboratory.

Overview

We are looking for a highly motivated individual to work on a project to identify novel strategies to delay onset and/or slow the progression of neurodegenerative diseases such as Huntington’s disease or Alzheimer's disease. The person who will join our team will initially work under the supervision of a senior technician until they are fully trained.

Responsibilities

Responsibilities include:

+ Prepare human brain samples for next-generation sequencing

+ Carry out techniques including RNA extraction, cDNA preparation, PCR, library preparation, and Western blot

+ Perform ATAC-seq or other epigenetic techniques

+ Use immunohistochemistry or in situ hybridization to stain tissue, and ImageJ and HALO to analyze data

Qualifications

Bachelor of Science degree with some familiarity in a laboratory setting is required. Educational emphasis in Neuroscience or Biology is strongly preferred.

The Rockefeller University is an equal opportunity employer – veterans/individuals with disabilities. Qualified applicants will receive consideration for employment without regard to characteristics protected by applicable local, state, or federal law, including but not limited to disability and protected veteran status.

The salary of the finalist selected for this role will be set based on various factors, including but not limited to organizational budgets, qualifications, experience, education, licenses, specialty, and training. The hiring range provided represents The Rockefeller University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

Compensation Range: Min

USD $50,000.00/Yr.

Compensation Range: Max

USD $55,000.00/Yr.