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At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: _“What would I do if this patient were my mom?”_ That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

The Senior Manager - Facilities Engineering is a key leadership role responsible for the strategic oversight, design, and continuous improvement of critical facility systems that support laboratory research and operational activities. This includes high-performance HVAC systems, cleanroom environments, and utilities infrastructure to ensure compliance with industry standards such as GMP, FDA, and ISO regulations. This individual will lead cross-functional initiatives to optimize system performance, implement energy-efficient solutions, and minimize downtime to maintain high-quality laboratory processes in a highly regulated environment. Additionally, the Senior Manager of Facilities Engineering will collaborate with Facility leadership to support all internal and external audits, ensuring continued compliance and operational excellence.

The Senior Manager - Facilities Engineering leverages technical expertise while collaborating with cross-functional teams, including quality assurance, project managers, and research scientists, to meet the evolving needs of the facility. This role leads the successful execution of projects such as system upgrades, facility expansions, and the construction of new buildings. Strong problem-solving skills, attention to detail, and dedication to maintaining safety and operational excellence are essential. Additionally, the Senior Facilities Engineering Manager will serve as the Subject Matter Expert (SME) for the Building Automation System (BAS), implementing solutions within the system to ensure laboratory environmental conditions are consistently maintained.

Job Responsibilities

+ Lead the design, operation, and optimization of critical facility systems, including Building Automations Systems, HVAC, cleanrooms, and utilities.

+ Ensure compliance with regulatory standards such as GMP, FDA, and ISO through robust documentation and system management.

+ Conduct regular inspections, testing, and calibration of systems to maintain operational efficiency and reliability working closely with the facility Sr. Manager and Technicians.

+ Direct the troubleshooting and resolution of technical issues, minimizing operational disruptions and downtime.

+ Identify and implement energy-efficient solutions to reduce operational costs while maintaining system performance.

+ Oversee the performance and maintenance of critical environments to support laboratory research and production.

+ Collaborate with Facility leadership to prepare for and support internal and external audits.

+ Act as the Subject Matter Expert (SME) for Building Automation Systems (BAS), ensuring laboratory environmental conditions are consistently maintained through system adjustments and optimizations. Lead all BAS upgrades, implementing advanced technology and modern controls strategies to enhance system performance and reliability.

+ Plan and manage system upgrades, facility expansions, and the construction of new buildings or infrastructure.

+ Coordinate with quality assurance teams to ensure facility systems align with operational and regulatory requirements.

+ Work closely with research scientists and operational teams to support laboratory processes and specialized facility infrastructure needs.

+ Monitor system performance and drive improvements to enhance safety, efficiency, and compliance.

+ Lead and participate in cross-functional team meetings to address facility needs and prioritize projects.

+ Manage vendor relationships and oversee contractor performance for system upgrades and installations.

+ Evaluate new technologies and make recommendations for system enhancements or replacements.

+ Ensure workplace safety by adhering to OSHA guidelines and implementing best practices for facility management.

+ Act as a liaison between the facilities team and other departments to address operational challenges and ensure smooth communication.

+ Oversee and manage all commissioning activities by developing and maintaining comprehensive documentation, including URS, SOPs, Standards, Policies, and Master Plans, to ensure facility assets and processes remain in a state of control. Ensure all activities align with and adhere to the quality management system.

+ Manage the creation and revision of system and facility drawings, ensuring compliance with FDA regulations.

+ Oversee predictive and preventive maintenance of electrical systems, as well as the design, review, and implementation of electrical system solutions.

+ Lead CAPEX planning, project execution, budget management, and provide updates to executive leadership.

Required Qualifications

+ Bachelor’s degree in Engineering (Mechanical, Electrical, or related field) and 8+ years of relevant experience; or a combination of education and at least 12 years of technical experience in facilities management within a regulated environment.

+ Proven experience with critical systems such as HVAC, cleanrooms, utilities, and Building Automation Systems (BAS), preferably in a GMP, FDA, or ISO-regulated industry.

+ Strong problem-solving and analytical skills, with the ability to interpret technical drawings, specifications, and regulatory requirements.

Preferred Qualifications

+ Professional certifications such as Certified Energy Manager (CEM), Facilities Management Professional (FMP), or similar credentials.

+ Experience managing facility expansion projects, system upgrades, or new construction within a life sciences or pharmaceutical environment.

+ Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.

Physical Demands

+ Must possess ability to sit, stand, and/or work at a computer for long periods of time.

+ May have exposure to blood-borne pathogens, extreme temperatures, high noise levels, fumes and bio-hazardous material/chemical including formalin in the lab environment.

+ Must possess ability to perform repetitive motion.

+ Ability to lift up to 30 pounds.

Training

+ All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

**Conditions of Employment:** Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Caris Life Sciences is a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine through quality and innovation.

Caris is committed to quality and excellence at our state-of-the-art laboratories. Learn more about our tissue lab and the advanced technologies that are helping improve the lives of cancer patients.