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We are seeking a passionate and driven Bioprocess Scientist to spearhead process development projects. This key scientific role requires a candidate with a strong background in upstream & downstream process development, and cross-functional collaboration. The Bioprocess Scientist will establish fermentation capabilities to support downstream purification and tech transfer. They will also conduct bench, pilot, and scale up on downstream purification processes and collaborate closely with Quality and Operations to launch new products.

JOB** **QUALIFICATIONS:

PhD in Chemistry, Biochemistry, Chemical Engineering, Microbiology or directly related field with 2 years of experience; or a Master’s degree with 2-4 years of combined academic and industrial experiences.

Will consider candidates with relevant industry experience in lieu of Ph.D. or Master’s.

KEY RESPONSIBILITIES

+ Support onboarding of bioreactors and supporting equipment.

+ Support internal and external technology transfer of upstream fermentations using fungal and yeast systems for expressing recombinant proteins.

+ Design experiments to optimize fermentations to support downstream purification process development and tech transfer.

+ Develop SOPs to support bioreactor operation, cleaning and maintenance

+ Develop downstream protein purification process at bench scale.

+ Scale-up purification process to pilot scale to facilitate tech transfer to manufacturing scale.

+ Troubleshoot and optimize processes for yield and meeting product requirements such as purity.

+ Develop quality control procedures and methods for new products.

+ Develop SOP’s, batch records, and processing documentation for scale-up and plant production.

+ Work closely with manufacturing team to facilitate process scale-up, commercial production and troubleshooting production issues.

+ Author reports, project related documents, summarize, and present scientific results.

+ Track progress against project plans, provide regular status updates and communicate issues with management.

+ Use scientific and product knowledge to support operations, quality and the technical operations team.

+ Stay informed about industry trends and emerging technologies in upstream expression systems and downstream purification development.

+ All other related duties as assigned.

SKILLS:

+ Strong knowledge of protein chemistry, biochemistry or protein engineering is required.

+ Experience in fermentation process development from flasks to fermenters, operation of bioreactors at bench-top to standalone scale, media composition and fermentation optimization.

+ Protein purification techniques such as precipitation, flocculation, and chromatography.

+ Experience using separation technologies such as centrifugation, tangential flow filtration, and depth filtration.

+ Experience in operating bioreactors and bench scale HPLC/FPLCs.

+ Ability to learn and operate pilot scale protein fractionation equipment: continuous flow centrifuge, ultrafiltration and chromatography.

+ Experience developing assays, immunoassays, and analytical techniques to support process development.

+ Analytical and problem-solving abilities.

+ Skilled at driving outcomes of experimental designs to ensure forward progress.

+ Open to suggestion and embraces the ideas of other team members.

+ Ability to independently scope R&D projects, identify key project milestones, and drive projects to conclusions.

+ Support team members in research planning, resource utilization, and collaborative learning.

+ Excellent written and oral communication skills to effectively communicate with technical and non-technical stakeholders.

+ Travel up to 10%, domestic and international.

LGI’s foundation began in 1916 as the Lauridsen Creamery, selling butter, eggs and poultry to the local community. Although our headquarters in Ankeny, Iowa, is not far from the old creamery in Dedham, Iowa, the company is now worldwide with more than fifty manufacturing and sales locations in twenty countries and sales in more than sixty countries.

Each company under the LGI umbrella is truly independent. They have the ability and the charge to be entrepreneurial, to seek out new markets, to develop new products and applications, and – above all - to discover new ways to add value through fractionation and novel application.

What’s more, because some LGI companies have offices and presence around the world, all LGI companies benefit from their exposure to new markets, new products, new applications and new thinking.