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Responsible for independently evaluating, selecting and applying standardized scientific procedures and techniques; contributes to the planning, design, execution and interpretation of experiments; makes detailed observations, records data and assists in preparation of reports, papers presentations, and new proposals; presents results/papers at technical meetings; may participate in the guidance/mentoring of junior staff.

Summary

The Genomics and Spatial Biology Collaborative Laboratory (CoLab) at SCRI is seeking a highly organized, detail-oriented Research Scientist II with impeccable bench skills related to spatial omics & NGS/third generation library preparations and analyses. The ideal scientist will have hands-on experience with both spatial biology workflows and DNA/RNA library preparations, as well as basic bioinformatic data compilation, formatting, and analysis.

The successful candidate will play an essential role in enabling cutting-edge pediatric research, assisting with core facility operations, and providing expert guidance and outreach to researchers. This position requires an understanding of genomics, transcriptomics, histology and spatial biology techniques, and a commitment to advancing scientific discovery by providing core services to SCRI laboratories. The Research Scientist II will provide innovative and rapid turn-around services for basic, translational, and clinical research, maximizing efficient use of CoLab equipment and helping to expand services to a wider customer base.

Key Responsibilities:

+ **Research & Development:**

+ Support the design, execution, and analysis of genomics and spatial biology experiments utilizing core facility technology.

+ Working with Research Scientist IV/Supervisor in the CoLab, develop and optimize protocols for NGS & long-read sequencing, spatial transcriptomics, and other advanced techniques.

+ Collaborate with researchers to design experiments, interpret data, problem solve, and publish results.

+ Keep up with technology landscape in the field and work towards keeping the core facility capabilities at the cutting edge.

+ Prepare reagents and assist with daily sample processing analysis.

+ Perform routine maintenance on laboratory instrumentation such as buffer exchange, calibration, and troubleshooting.

+ **Core Facility Operations:**

+ Participate in daily operations of the Genomics and Spatial Biology CoLab, ensuring high standards of quality, organized inventory controls, and accurate record keeping.

+ Actively monitor core supplies inventory and work with Research Scientist IV/Supervisor to identify supply order needs.

+ Ensure projects are completed and billed on schedule.

+ Operate and maintain advanced sequencing platforms, spatial transcriptomics equipment, and other core facility technologies.

+ Ensure compliance with safety regulations, quality control, and standard operating procedures.

+ Support core facility technology promotions and relevant events

+ **Data Management & Analysis:**

+ Maintain detailed electronic lab notebook on all experiments performed & provide basic QC reports on completed core services.

+ In partnership with computing and data science core at SCRI, support data acquisition and management in the genomics and spatial biology area.

+ Collaborate in the design, development, and implementation of data management and data science solutions.

+ **Collaboration & Communication:**

+ Foster collaborative relationships with internal and external researchers, promoting the use of core facility services.

+ Support the development of scientific reports, grant applications, and publications.

+ Represent the core facility at conferences, seminars, and institutional meetings as needed.

+ Participate in training technicians and trainees, including students

Required Education and Experience

Bachelor’s Degree in an engineering or scientific discipline; may require a Master’s Degree for certain lab specialties.

Minimum of two (2) years’ experience in a related area/laboratory setting.

Required Credentials

N/A.

Preferred

Master’s Degree in applicable field/research specialty highly preferred.

Significant experience conducting research in area of specialization.

Some experience with laboratory management.

Compensation Range

$31.28 - $46.93 per hour

Salary Information

This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.

Disclaimer for Out of State Applicants

This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors **.**

Benefits Information

Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website www.seattlechildrens.org/careers/benefits .

About Us

Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE

Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.

As a Magnet designated institution, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.

Our Commitment

Seattle Children’s welcomes people of all experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our patients and families. Our organization recruits, employs, trains, compensates, and promotes based on merit without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves.

Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.