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The Position

Are you an expert in Oncology Imaging? Do you have an interest in drug development, as well as knowledge and practical experience in the field of imaging technologies and image analysis? We are offering an exciting opportunity to join the global department Translational Medicine & Clinical Pharmacology (TMCP) at our sites in Biberach (Germany), Ingelheim (Germany) or Ridgefield (US).

TMCP is a global organization within the Innovation Unit that builds understanding of diseases and drugs by developing and applying innovative translational strategies (including biomarkers, clinical pharmacology, pharmacometrics and digital approaches) across the entire clinical development pipeline.

We drive projects fast and stringently to informed decisions on first-in-man, proof of pharmacological principle (PoPP), proof of clinical principle (PoCP) and proof of clinical concept (PoCC) up to submission. To generate an integrative understanding of the dose-exposure-biomarker-response/clinical end-point relationship and to maximize translational knowledge generation, we are applying state-of- the-art technologies and data analytics, support start of development decision points (SoDs) and enable Precision Medicine to deliver differentiated therapies for patients.

This position can be filled in Germany or USA.

If you want to apply for the position in USA, please use this link: _coming soon_

If you want to apply for the position in Germany, Ingelheim or Biberach, click "Apply now".

Tasks & responsibilities

+ In your subject matter expert role, you will be a part of oncology drug development projects from clinical phase I to phase III trials by providing strategic and operational support for implementing imaging-based efficacy endpoints and clinical imaging biomarkers.

+ Moreover, you will work in close collaboration with internal stakeholders from Clinical Operations, Medicine, and Statistics as well as with external academic partners and imaging CROs.

+ In addition, you will evaluate and implement novel imaging methods (e.g. Positron Emission Tomography (PET) with novel radiotracers) and image analysis technologies (e.g. radiomics) to investigate drug biodistribution and therapeutic response in patients.

Additional tasks & responsibilities for Senior Principal Scientist

+ As a Senior Principal Scientist, you will act as the internal reference contact for specific clinical imaging approaches in oncology.

+ Furthermore, you will design and lead experimental medicine studies to validate clinical imaging biomarkers in collaboration with internal and external partners.

+ You will establish a network of leading academic and industry partners to ensure a continuous exchange about oncology imaging/image analysis methodologies across projects.

Requirements

+ PhD or equivalent in a biomedical or imaging-related field

+ Experience in clinical imaging in the fields of radiology, nuclear medicine, drug development or clinical pharmacology using multiple imaging modalities (e.g. Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET))

+ Pharma or imaging CRO experience is a plus

+ Understanding of clinical trial designs and knowledge about implementing oncology-specific imaging endpoints (e.g., RECIST 1.1, RANO)

+ Knowledge about relevant regulatory frameworks applicable for clinical imaging and drug development (e.g., Good Clinical Practice (GCP), FDA industry guidance)

+ Able to project opinions and knowledge with confidence and diplomacy when interacting with all levels of internal stakeholders and external partners

+ Innovative, self-directed mindset with good communication skills

+ The international nature of the task requires excellent English - both spoken and written

Additional Requirements for Senior Principal Scientist

+ Long-term experience in the field of clinical oncology imaging with several years of working experience in the pharmaceutical industry or imaging CRO

+ Track record of successful implementation of submission relevant efficacy endpoints and the use of imaging biomarkers across clinical drug development stages

+ Excellent leadership skills, successfully proven in project team settings, and demonstrated ability to deliver business critical results

Ready to contact us?

If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330 or via mail: [email protected]

Please submit your application documents in English.

Discover our Biberach site: xplorebiberach.com

All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.