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The Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute (DFCI) is at the forefront of advancing modeling science and research. Our focus is on utilizing patient-derived cell lines (PDCL), organoids (PDO), xenografts (PDX), and patient cells in functional precision medicine (FPM) studies. Located in Boston, DFCI is a leader in cancer research and patient care, committed to conquering cancer, HIV/AIDS, and related diseases. We are dedicated to fostering an inclusive, diverse, and equitable environment, providing compassionate care, and promoting public health, especially among high-risk and underserved populations.

Position Overview:

We are seeking a Research Scientist to join our dynamic team. The successful candidate will contribute to our understanding of precision medicine, cancer biology, treatment, and diagnostics across all cancer types in adults and children. This role involves applying cutting-edge techniques to develop patient-derived cancer models and collaborating with academic and biopharma industry partners.

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Center for Patient Derived Models (CPDM) - Dana-Farber Cancer Institute | Boston, MA

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Key Responsibilities:

- Design and execute experiments aligned with the center’s mission to advance functional precision medicine.

- Develop and conduct in-vitro drug screens using advanced methods and complex patient-derived models.

- Perform preclinical in-vivo assays in mouse models as needed.

- Handle and process patient tissue samples.

- Analyze experimental data, interpret results, and prepare reports, grant applications, and presentations.

- Stay updated with relevant literature and research publications.

- Supervise and mentor junior staff.

- Develop, modify, and improve standard operating procedures.

- Utilize computer-interfaced equipment and automation for research tasks.

Qualifications:

- PhD or doctoral degree in biomedical/bioengineering or MD with research experience preferred.

- 4-5 years of postgraduate experience is preferred.

- Proven supervisory experience in leading and developing team members.

- Strong verbal and written communication skills, with experience in writing grants, manuscripts, and reports.

- Recent benchwork experience in cellular and molecular biology, in vivo and in vitro cancer models, and cancer genomics.

- Familiarity with genomic databases and ability to understand new concepts quickly.

- Innovative approach to process development and goal achievement.

- Experience in manuscript and grant/proposal writing is required.

- Excellent organizational and data management skills.

- Proficiency in graphing software (Microsoft suite, Graphpad/Prism) and basic coding (R/Python) is highly desirable.

What We Offer:

- Comprehensive training and mentorship opportunities.

- A supportive and collaborative work culture.

- Opportunities to work on diverse and exciting projects with clinicians, academic researchers, and industry partners.

- Opportunities to publish work in various formats.

- Exposure to cutting-edge technologies and industry trends.

Join us in making a significant impact in the field of cancer research and precision medicine. Apply today to be part of our innovative team at DFCI.

**ADDITIONAL INFORMATION:** Please include a statement of interest and three references with your resume as a single document.

**SUPERVISORY RESPONSIBILITIES:** Provide some supervision and training of technicians, postdoctoral fellows and students.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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