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Job Description

_Roles & Responsibilities:_

A postdoctoral fellow position is available in the new laboratory of Dr. Liheng Wang, at Icahn School of Medicine at Mount Sinai in New York City.

Dr. Wang is looking for postdoctoral candidates with strong skill sets in metabolism, biochemistry, cell biology and the enthusiasm to establish a highly collaborative, friendly team. The ongoing research in Dr.Wang’s lab focus on the transcriptional regulation of hepatic glucose and lipid metabolism in the context of type 2 diabetes (T2D), obesity and Non Alcoholic Fatty Liver Disease (NAFLD). Combining DNA pulldown and mass spectrometry techniques, they have discovered several new transcription factors that potentially regulate hepatic glucose and lipid metabolism. They will further explore the functions of these transcription factors on the transcriptional regulation of liver metabolism, to explore and understand the underlying mechanisms at the molecular, cellular, tissue, and physiological levels, and eventually to develop efficient and safe interventions for preventing and treating metabolic diseases. Her recent publications include Cell Metabolism, Journal of Hepatology, Journal of Clinical Investigation etc (https://www.ncbi.nlm.nih.gov/myncbi/1jCqszge5p3kN /bibliography/public/). The common technologies used in the lab include transgenic mouse models, human genetics, metabolic studies, stem cell biology, next generation sequencing, and a variety of molecular and cell biology techniques. Her group will work collaboratively with other groups in Diabetes, Obesity, and Metabolism Institute (DOMI) and other divisions at Mount Sinai, as well as other universities in New York City (e.g. Columbia University, Weill Cornell, Albert Einstein School of Medicine). For further information, please contact Dr. Wang ([email protected]).

_Requirements:_

Laboratory:

• Plan and execute studies to assess mouse metabolic phenotypes and liver metabolism.

• Adapt and apply methods to study hepatocyte glucose and lipid metabolism in vitro and in vivo.

• Apply methods/new techniques to investigate the molecular mechanisms on transcriptional regulation, signaling transduction and pathogenesis of T2D and NAFLD.

• Work with other team members to manage animal colony.

Data management:

• After training, responsible for data management and sharing for the project.

• Working with other team members to maintain and update data storage.

Administrative:

• Participate in internal and external meetings and conferences related to project.

• Work with team members to ensure protocols and resources are generated, shared and updated in a timely fashion.

Qualifications

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Responsibilities

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About Us

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

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About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation Statement

Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.