• Sr. Downstream Processing Technician

    Actalent (St. Louis, MO)


    Job Title: Downstream Processing TechnicianJob Description

     

    The Downstream Processing Technician is responsible for supporting the manufacture of Commercial and Clinical Biologics, adhering to Current Good Manufacturing Practices (cGMPs). The role involves various functions related to Downstream processes, including purification, filtration, and chromatography. The Technician will manufacture buffers and simple bulk reagents and participate in process improvement projects.

    Responsibilities

    + Review all area documents.

    + Manage the WNS.

    + Assist in the manufacture of controls and calibrators, completing batch records in accordance with cGMPs.

    + Perform in-process assays using equipment such as spectrophotometers, pH meters, and clinical analyzers.

    + Weigh, transfer, and mix chemicals as required.

    + Conduct product filtrations.

    + Clean and steam steel tanks (CIP) / (SIP).

    + Prepare glassware and steel tanks for sterilization and operate autoclave.

    + Maintain lab equipment, including pumps, pH meters, and flow meters.

    + Keep department lead or manager updated on all issues.

    + Monitor stocks of common lab supplies.

    + Perform other job duties as required.

    + Respond to Emergency notifications.

    + Be flexible with hours, including weekends.

    Essential Skills

    + Proficiency in cleanroom procedures and aseptic technique.

    + Experience in laboratory settings and chemical handling.

    + Minimum of 2 years of work experience in manufacturing, operation, production, lab setting, or a related field.

    Additional Skills & Qualifications

    + Preferred: Experience in a cGMP regulated environment and aseptic technique.

    + Bachelor's Degree in Science, preferably in a STEM field.

    + Knowledge of cGMP practices, aseptic techniques, and chemical concepts.

    + Subject Matter Expert on downstream processing steps.

    Work Environment

    The role operates in clean room/aseptic suites where gowning is required, including wearing a full gowning suit (bodysuit, gloves, hair & beard nets, face covers, and safety glasses). Certain items are prohibited such as makeup, jewelry, nail polish, cologne/perfume, and scented lotions or hair care products. The position involves rotating 12-hour shifts, with both day and night options available, working 7 days out of a 2-week period. Technicians must be able to lift a minimum of 25 lbs independently and stand for 80% of the shift.

    Pay and Benefits

    The pay range for this position is $27.00 - $31.00/hr.

     

    Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

     

    • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)

     

    Workplace Type

     

    This is a fully onsite position in Saint Louis,MO.

     

    Application Deadline

     

    This position is anticipated to close on May 28, 2025.

    About Actalent

    Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

     

    The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

     

    If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email [email protected] (%[email protected]) for other accommodation options.