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The research in D'Andrea lab and Center for DNA Damage and Repair (CDDR) is focused on studying the DNA repair pathways and investigating the inhibitors of these pathways as novel drugs for the treatment of cancer patients. We employ a wide range of novel technologies for the measurement of DNA damage response in cancer cell lines and patient-derived organoid models, including cytotoxicity measurements, and proteomic biomarker measurements.

We are seeking a Research Technician who will assist the staff scientists/ postdoctoral fellows in performing scientific research, of varying complexity. In general, this individual will assist in the set-up, operation, and maintenance of laboratory instruments and equipment, monitoring and performing experiments, making observations, and calculating and recording results. The individual will be trained and will be expected to work independently under general supervision. The individual will be an integral member of the research group and work collaboratively with members of the lab. The position will involve performing routine laboratory techniques related to the translational projects.

Students interested in pursuing M.D., Ph.D., or M.D./Ph.D. training will benefit most from this laboratory experience. They will develop the ability to think critically and design careful and well-controlled experiments. Technicians will have the opportunity to be co-authors on manuscripts published in the laboratory.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

+ General laboratory maintenance such as ordering, and maintaining the lab supplies

+ Maintain a detailed notebook of all work-related activities

+ Culture various cancer cell lines and organoid models and perform drug sensitivity assays

+ Process primary tissue from patients for organoid generation

+ Perform western blots, DNA damage assays and DNA replication assays

+ Pick up or drop off tissue samples from the laboratories/hospitals within the campus

+ Minimum Bachelor's dgree required with a major in biology or chemistry preferred

+ Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.

+ Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.

+ Ability to analyze information and use logic to address work-related issues and problems.

+ Must have attention to detail and be thorough in completing work tasks.

+ Ability to work within a team environment

+ Some tissue culture experience is a plus.

+ We are seeking candidates with at least two years of availability.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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