• Research Scientist II, Biochemistry & Molecular…

    UTMB Health (Galveston, TX)


    Research Scientist II, Biochemistry & Molecular Biology Research Staff

     

    Galveston, Texas, United States

     

    Research Academic & Clinical

     

    UTMB Health

     

    Requisition # 2502265

     

    The Mass Spectrometry Facility (MSF)at UTMBis a research facility located within theDepartment of Biochemistry and Molecular Biologyand is seeking several a new team member focused on proteomics or protein analysis using LCMS . The MSFcontributes to scientific projects with leaders in neurobiology, sarcopenia of aging, rare and infectious diseases, burn research, cancer biology, translational research, and projects with NASA. The positions will be part of a cutting-edge a Mass Spectrometry Facility team and requires the ability to participate in multi-disciplinary research in a collaborative setting. The MSF provides fee-for-service access to advanced technologies for proteomics, macromolecular, small molecule, and metabolomics acquisition via MS and LC/MS/MS (https://www.utmb.edu/msf).

     

    The purpose of this position is to assist in the preparation and analysis of samples submitted to the Mass Spectrometry Core Facility (MSF) at the University of Texas Medical Branch at Galveston (UTMB). We are looking for curious and motivated individuals with strong backgrounds in sample preparation methods for proteins and/or proteomics Research Scientist II position; candidates with a Ph.D are preferred but BS and MS will be considered based upon practical experience. The position will be part of a high-energy, cutting-edge Mass Spectrometry Core Facility team.

     

    The incumbent in this position will be primarily responsible for preparing samples from a variety of complex biological sources, quality control of sample preparation, and routine maintenance of several HPLC systems. The position will require performing sample preparation of proteins and/or small molecules from biological matrices (cells, tissues, serum, etc.) prior to MS analysis. Strong oral and written communication skills are required. In addition, the incumbent is required to keep a detailed laboratory notebook, contribute to general orderliness of the laboratory and support lab health and safety compliance. The incumbent will be required to write a variety of technical and/or project reports as well as document newly developed methods.

    _MAJOR DUTIES / CRITICAL TASKS_** **_:_

    • Under general supervision, performs routine and non-routine research assignments and experiments of moderate complexity.

    • Plans, coordinates, provides setup and conducts standard research experiments following general technical instructions.

    • Prepares biological assays and conducts quantitative and qualitative analysis.

    • Perform regular Quality control checks on LC’s, current inventory includes one Waters Acquity, two Agilent 1260 LC’s, and 2 Thermo 3000nano RSLC’s

    • Maintains records of all tests performed and data collected and provides preliminary analysis of results.

    • Orders consumables, parts and service as required to maintain the Facility.

    • Maintains lab inventory of supplies and equipment.

    • Makes modifications to research procedures as determined by Principal Investigator.

    • Participation in multi-disciplinary research in a collaborative setting.

    • Performs related duties as required.

    Desired, but not required, skills:

    • Operating instruments and assisting with calibration, troubleshooting and maintenance including providing quality control measurements on a variety of MS instruments. Current instrumentation includes: Thermo Orbitrap Eclipse and Fusion.

    • Analyzing complex qualitative/quantitative proteomic datasets through a variety of software packages (Proteome Discoverer, Fragpipe, MASCOT, MaxQuant, Perseus, Scaffold, Skyline, Biopharma Finder, MASH, TopPic, ProSight, etc).

    MINIMUM QUALIFICATIONS:

    + Ph. D, M.D, D.O., or D.V.M in related field and one year of related experience.

    SALARY:

    Commensurate with experience

     

    Equal Employment Opportunity

     

    UTMB Health strives to provide equal opportunity employment without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, genetic information, disability, veteran status, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. As a Federal Contractor, UTMB Health takes affirmative action to hire and advance protected veterans and individuals with disabilities.

     

    Compensation