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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub** **Function:

Translational Discovery & Development Biomarkers

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Director, Biomarker - Aging and Metabolism to be in Spring House, PA.

Purpose:

This individual will play a critical role in driving biomarker strategy and advancing translational research efforts to support drug discovery and development. This position leverages deep expertise in preclinical and clinical biomarkers to accelerate the development of novel therapeutics targeting age-related degenerative diseases, including cardiovascular pathology, thrombosis, and sarcopenic obesity. Additionally, this role contributes to Johnson & Johnson therapeutic strategies across neuroscience, immunology, and oncology.

You will be responsible for:

• Biomarker strategy to support sarcopenic and aging-related diseases, collaborating across J&J’s Cross-Therapeutic Area (TA) Small Molecule, Biologics, and MedTech teams.

• Drive biomarker development efforts for early- and late-stage drug candidates, ensuring robust clinical translation.

• Provide scientific and strategic leadership, supporting cross-functional teams and external research collaborators.

• Oversee preclinical and clinical biomarker implementation, integrating cross-TA exploratory efforts to evaluate novel assets and repurpose J&J pipeline candidates.

• Biomarker support for the regulatory filing of macitentan 75 in pulmonary arterial hypertension.

• Maintain scientific leadership, fostering innovation, collaboration, and visibility through publications, external engagement, and strategic partnerships.

• Strategic Impact: The Biomarker Director – Aging & Metabolism plays a vital role in shaping preclinical and clinical development strategies to address unmet clinical needs in aging-related pathologies.

• Defining and executing a comprehensive vision for biomarker-driven preclinical and clinical programs in aging and metabolism.

• Collaborating across therapeutic areas to develop and optimize clinical development plans (CDPs).

• Building and strengthening relationships with Key Opinion Leaders (KOLs), enhancing global scientific impact and visibility.

• Exhibit self-awareness, a learning mindset, and the ability to build effective relationships built on a foundation of trust with colleagues across the business.

• Build and maintain strong collaborations within the TA (TA R&D, Clinical Development, DPDS) and partnering functions (Regulatory, Global Development, Medical Affairs, Commercial).

• Share responsibility, as a member of the TA, for developing a world-class culture within the Cardiopulmonary TA and in the wider organization.

Qualifications / Requirements:

Education:

• Bachelor’s degree is required

• Master’s degree or PhD is preferred

Required:

• Minimum of 10 years’ experience working in Pharmaceutical, Biotechnology or Medical Device/Diagnostics industry

• Experience with preclinical and clinical biomarkers for metabolic and cardiovascular indications

• Demonstrated experience in managing high-volume workload and prioritization

• Excellent knowledge of standard office software (e.g., Outlook, MS office, etc.,) and other computer systems and technologies (e.g., Zoom/Teams, SharePoint, etc.,)

• Ability to work effectively independently and collaborate in a global team environment

• Ability and willingness to work in a global matrix environment with cross-functional, international teams

• Excellent communication skills

• Travel up to 10% of the time (domestic and international), defined by business needs.

Preferred:

• Previous team leadership in a matrix organization

• Track record of publications in the cardiovascular and metabolic space

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([email protected]) or contact AskGS to be directed to your accommodation resource.

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