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At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: _“What would I do if this patient were my mom?”_ That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

The Digital Pathology Analyst is responsible for assisting in development of Digital Pathology Operations workflows for the clinical business, under limited supervision. This includes developing, customizing and executing efficient whole-slide imaging and analysis in the clinical space. The Analyst II will be expected to design, and, in collaboration with pathologists and other departments, implement cutting-edge technologies for the imaging and digital interpretation of clinical tissue samples.

Job Responsibilities

+ Independently design algorithms in one or more digital pathology analysis software packages and be expected to document algorithm development methods and support laboratory colleagues using these methods

+ Develop new quantitative image analysis protocols for clinical interpretation of histological stains, immunohistochemistry stains, immunofluorescent stains, and in situ hybridization stains

+ Perform technical functions for scanning, including slide orientation, setup, annotation and identifying regions of interest as a part of workflow development.

+ Evaluate and validate new computational approaches in digital pathology to support the clinical workflow.

+ Assist with the preparation of digital images for various downstream pipelines including converting digital images to static tiff or jpg formats, if needed.

+ Work in a deadline-oriented manner, and submit high quality work on time, while handling several concurrent, fast-paced projects and maintaining data integrity.

+ Manage commercial software updates

+ Maintains an understanding of the current best practices and emerging analytical technologies for image acquisition and analysis.

+ Communicate with vendors to facilitate resolution of issues with digital pathology applications, instrumentation and software.

+ Maintain confidentiality of all patient information in accordance with federal, state and local guidelines and regulations.

+ Document projects, algorithms and results in detail with the ability to proofread/fact-check and record results in laboratory information systems.

+ Train users in the use of viewer software or IMS that allow navigation, magnification changes, annotations as well as telepathology.

+ Collaborate with inter-departmental staff to ensure streamlined usage of different WSI platforms and analysis software.

CLIA/NYS/CAP/ISO 15189 2012

Each individual performs only those high complexity tests that are authorized by the laboratory director and require a degree of skill commen­surate with the individual’s education, training or experience, and technical abilities.

Each individual performing high complexity testing must:

+ Follow the laboratory’s proce­dures for specimen handling and proc­essing, test analyses, reporting and maintaining records of patient test results;

+ Maintain records that dem­onstrate that proficiency testing sam­ples are tested in the same manner as patient specimens;

+ Adhere to the laboratory’s quality control policies, document all quality control activities, instrument and pro­cedural calibrations and maintenance performed;

+ Follow the laboratory’s estab­lished policies and procedures when­ever test systems are not within the laboratory’s established acceptable lev­els of performance;

+ Be capable of identifying problems that may adversely affect test perform­ance or reporting of test results and ei­ther must correct the problems or im­mediately notify the general super­visor, technical supervisor, clinical consultant, or director;

+ Document all corrective actions taken when test systems deviate from the laboratory’s established perform­ance specifications; and

+ Perform high complexity testing under the onsite, direct supervision of a general supervisor as defined in the CLIA regulations.

Required Qualifications

+ MS in biological science/engineering or in a field related to signal/image processing, pattern recognition, and/or computer vision, with 1-3 years of experience in a laboratory setting.

+ Experience with whole-slide imaging in support of histopathology data collection and analysis.

+ Knowledge of image analysis (e.g. filtering signal channels, object segmentation, feature detection and classification).

+ Prior experience with one or more of MATLAB, CellProfiler, Aperio, HALO, QuPath or Visiopharm is highly desirable.

+ Experience with PC based graphics software packages, database, spreadsheet, and communications software applications.

+ Familiarity with histological analysis techniques, tissue morphology and microscopy.

+ Knowledge of laboratory safety and quality control procedures and regulations.

Preferred Qualifications

+ Ability to multi-task and work in a fast-paced, deadline driven environment.

+ Effective verbal and written communication skills. Proven attention to detail with effective organizational skills.

+ Effective interpersonal and team skills.

+ Proficient in Microsoft Office Suite and Internet for business use.

+ Drive for Results (Service, Quality, and Continuous Improvement) – Ensure procedures and processes are in place that lead to delivery of quality results and continually reassess their effectiveness to achieve continuous improvement.

+ Requires a high degree of care and attention with strict adherence to defined clinical testing protocols.

+ Communication – Proficient verbal and written communication skills. Willingness to share and receive information and ideas from all levels of the organization in order to achieve the desired results.

+ Teamwork – Commitment to the successful achievement of team and organizational goals through a desire to participate with and help other members of the team.

Physical Demands

+ Must possess ability to sit, stand, and/or work at a computer for long periods of time.

+ May have exposure to blood-borne pathogens, extreme temperatures, high noise levels, fumes and bio-hazardous material/chemicals including formalin in the lab environment.

+ Visual acuity and analytical skill to distinguish fine detail. Ability to pass a visual color discrimination test.

Required Training

+ All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

+ This position requires periodic travel and some evenings, weekends and/or holidays.

**Conditions of Employment:** Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Caris Life Sciences is a leading innovator in molecular science and artificial intelligence focused on fulfilling the promise of precision medicine through quality and innovation.

Caris is committed to quality and excellence at our state-of-the-art laboratories. Learn more about our tissue lab and the advanced technologies that are helping improve the lives of cancer patients.