"Alerted.org

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 114,000 colleagues serve people in more than 160 countries.

ABOUT ABBOTT

Abbott is a global healthcare leader, creating breakthrough science to improve people’s health. We’re always looking towards the future, anticipating changes in medical science and technology.

Our diagnostic solutions are used in hospitals, laboratories, and clinics around the globe. The crucial information derived from our tests, instruments and informatics systems are often the first step in patient care decision making for hundreds of health conditions from heart attacks to blood disorders to infectious diseases and cancers.

WORKING AT ABBOTT

At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You’ll also have access to:

+ Career development with an international company where you can grow the career you dream of.

+ Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year

+ An excellent retirement savings plan with high employer contribution

+ Tuition reimbursement, the Freedom 2 Save (https://www.abbott.com/corpnewsroom/strategy-and-strength/tackling-student-debt-for-our-employees.html) student debt program and FreeU (https://www.abbott.com/corpnewsroom/strategy-and-strength/college-degree-for-free-its-possible-with-freeu.html) education benefit - an affordable and convenient path to getting a bachelor’s degree.

+ A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune.

+ A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists.

THE OPPOURTUNITY

We have an exciting opportunity for an Innovative **Research Associate –** **Chemistry/Biochemistry** within our Abbott Rapid Diagnostics business located at **San Diego, CA** . We are seeking a highly motivated and skilled Oligonucleotide Research Associate to join our dynamic research and development team. The successful candidate will play a key role in the synthesis, purification and characterization of oligonucleotide for diagnostic application and related fields.

Abbott Rapid Diagnostics (formerly Alere) is part of Abbott’s Diagnostics family of businesses, bringing together exceptional teams of experts and industry-leading technologies to support diagnostic testing which provides important information for treatment and management of diseases and other conditions.

WHAT YOULL DO

+ Operate and maintain automated oligonucleotide synthesizers to produce DNA and RNA oligos of varying lengths and modifications.

+ Purify synthesized oligonucleotides using reverse-phase or ion-exchange HPLC or cartridge-based methods, as appropriate

+ Conduct quality control testing by utilizing analytical HPLC, UV spectroscopy, and mass spectrometry

+ Accurately document synthesis protocols, yields, and quality control data in laboratory records.

+ Manage inventory of raw materials, reagents, and consumables required for oligo production.

+ Collaborate closely with assay development scientists to ensure timely delivery of high-quality oligos for research and development purposes.

+ Execute biochemistry experiments under supervision

+ Execute sample preparation protocols under supervision

+ Adhere to laboratory safety protocols and maintain compliance with quality standards.

BASIC QUALIFICATIONS

+ B.S. in Chemistry, Biochemistry, Analytical Chemistry, or a closely related field.

+ Experience in oligonucleotide synthesis, cleavage and deprotection techniques.

+ Minimum 2 years experience working in chemistry or biochemistry lab

+ Skilled in developing and implementing analytical and biophysical methods for characterizing raw materials and final oligonucleotide products.

+ Capable of performing routine maintenance and calibration of laboratory instrumentation.

+ Strong communication, analytical, and problem-solving skills, with a keen attention to detail.

PREFERRED QUALIFICATIONS

+ Experience with post-synthetic modification and conjugation of oligonucleotides using various fluorophores and ligands.

+ Hands-on experience operating and maintaining automated oligonucleotide synthesizers; direct experience with Dr. Oligo and MerMade systems is a plus.

+ Strong familiarity with solid-phase synthesis chemistry and common oligonucleotide modifications (e.g., fluorophores, quenchers, phosphorothioates).

+ Proficient in oligonucleotide purification using techniques such as reverse-phase and ion-exchange HPLC.

+ Experience with analytical techniques including UV-Vis spectrophotometry, HPLC, and LC-MS.

+ Familiarity with various HPLC systems such as Agilent, Waters, and ÄKTA Pure is a plus.

+ Solid understanding of solid-phase organic synthesis principles, particularly as applied to oligonucleotide chemistry.

+ Experience with sample preparation techniques and basic biochemical techniques.

The base pay for this position is $72,100.00 – $114,700.00. In specific locations, the pay range may vary from the range posted.

An Equal Opportunity Employer

Abbot welcomes and encourages diversity in our workforce.

We provide reasonable accommodation to qualified individuals with disabilities.

To request accommodation, please call 224-667-4913 or email [email protected]