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The Jones Lab is developing next-generation covalent chemical biology with the objective of expanding the druggable proteome. We seek a highly motivated individual to join our collaborative research efforts as a POSTDOCTORAL RESEARCH FELLOW who will work on chemical biology projects directed towards the development of novel therapeutic modalities.

We are based at Dana-Farber Cancer Institute in Longwood Center, and we have access to state-of-the-art facilities for chemistry, biophysics, biochemistry, structural biology, and mass spectrometry.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

+ Develop and apply biochemical, biophysical, and cellular assays to enable the development of chemical probes suitable for cellular and in vivo pharmacological validation

+ Screen compounds; analyze and interpret data

+ Explore and elucidate molecular modes-of-action of chemical probes

+ Maintain accurate lab records and documentation

+ Contribute to publications and grant proposals.

+ Stay current with scientific advances in the fields of chemical biology and screening technologies, and apply emerging techniques and insights to their own research

+ PhD degree in chemical biology or a related discipline

+ Expert in protein preparation, biochemical assay development and compound screening

+ Expert in chemical biology techniques used to assess interactions between proteins and small molecules

+ Experience in cell-based assay development, compound screening and immunoblot

+ Experience in chemoproteomics is desirable

+ Excellent communication and presentation skills

+ Evidence of consistent scientific innovation. Proven track record of publications in peer reviewed journals

+ Able to work independently as well as in a collaborative team environment

+ Excellent organizational and prioritization skills. Strong attention to detail

+ Able to collect and analyze experimental data, prepare research publications, and communicate results

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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