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Details

Title Postdoctoral Fellow

School Faculty of Arts and Sciences

Department/Area Molecular and Cellular Biology/Applied Physics/SEAS

Position Description

Our lab is developing a series of cutting-edge methods to visualize cellular organization. As one example, we are using time-resolved cryo-vitrification (both cryo-plunging and high-pressure freezing) to visualize the nanoscale dynamics of cellular response to stimuli. In another direction, we are developing multicolor electron microscopy using the principle of “cathodoluminescence” – emission of light triggered by excitation with an electron beam. The advertised position involves further development of these and related methods as well as applications of these new technologies to address questions in the fundamental cell biology of transmembrane signaling through G-protein-coupled receptors and the formation of biomolecular condensates.

Basic Qualifications

Competitive applicants would typically have expertise in one or more of the following areas:

-Biophysical instrumentation development: optical and mechanical design, simulation, development and control

-Optical imaging; Single-molecule fluorescence and FRET ; Lasers; Pump-probe experiments

-Biophysics of cell signaling and stress response; Biomolecular condensates; G-protein-coupled receptors (GPCRs); Cell and molecular biology

-Cryo-vitrification via cryo-plunging and high-pressure freezing; Time-resolved freezing

-Microfluidics; design, simulation, prototyping, fabrication and testing of fluidic devices

-Electron microscopy (cryo and regular) for structural and cell biology; Cathodoluminescence

Additional Qualifications

Special Instructions

Letters of recommendation are not required at the time of application; however letters will be collected for finalists. Candidates should submit with their application contact information for three references from experts at the ladder faculty ranks or highly accomplished senior researchers from corporations or research institutes.

Please include the following items as part of your application:

+ Cover Letter

+ Curriculum Vitae

+ Summary of research experience and interests.

+ Name and contact information for 3 references.

Contact Information

Professor Maxim Prigozhin

Northwest Lab Building

52 Oxford Street

Cambridge, MA 02138

Debra Maddalena (Administrator)

[email protected]

Contact Email [email protected]

Minimum Number of References Required 3

Maximum Number of References Allowed 3

Keywords

EEO/Non-Discrimination Commitment Statement

Harvard University is committed to equal opportunity and non-discrimination. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard’s academic purposes.

Harvard has an equal employment opportunity (https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation\_statement.pdf) policy that outlines our commitment to prohibiting discrimination on the basis of race, sex, ethnicity, color, national origin, religion, disability, or any other characteristic protected by law or identified in the university’s non-discrimination policy (https://provost.harvard.edu/sites/g/files/omnuum3356/files/2025-07/non-discrimination\_and\_anti-bullying\_policies.pdf) . Harvard’s equal employment opportunity policy and non-discrimination policy help all community members participate fully in work and campus life free from harassment and discrimination.

Supplemental Questions