• Sr. Downstream Processing Technician

    Actalent (St. Louis, MO)


    Chemistry Processing Technician

    Job Description

    We are seeking a dedicated Downstream Processing Technician to support the manufacture of Commercial and Clinical Biologics. The role involves following Current Good Manufacturing Practices (cGMPs) and performing various functions related to purification and filtration processes, including handling large-scale chromatography and bioreactors.

    Responsibilities

    + Review all area documents and ensure compliance with standards.

    + Assist in the manufacture of controls and calibrators, completing batch records in adherence to cGMPs.

    + Conduct in-process assays using equipment such as spectrophotometers, pH meters, and clinical analyzers.

    + Weigh, transfer, and mix chemicals as required for production.

    + Perform product filtrations and clean/steam steel tanks (CIP/SIP).

    + Prepare glassware and steel tanks for sterilization and operate autoclave.

    + Maintain lab equipment, including pumps, pH meters, and flow meters.

    + Keep department lead or manager informed of all relevant issues.

    + Monitor stocks of common lab supplies and respond to emergency notifications.

    + Work flexible hours, including weekends, as needed.

    Essential Skills

    + Bachelor's Degree in a STEM-related field.

    + Minimum of 2 years of work experience in manufacturing, operation, production, or a lab setting.

    + Proficiency in aseptic techniques and knowledge of cGMP practices.

    + Experience with large-scale chromatography and bioreactors.

    Work Environment

    The position requires working in cleanroom/aseptic suites with a night shift schedule from 6:15 pm to 6:45 am on rotating 12-hour shifts. Employees must adhere to gowning requirements, including wearing a full gowning suit, and be able to lift a minimum of 25 lbs independently. The role demands standing for 80% of the shift. The work environment prohibits makeup, jewelry, nail polish, cologne/perfume, and scented products.

    Pay and Benefits

    The pay range for this position is $32.20 - $32.20/hr.

     

    Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

     

    • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)

     

    Workplace Type

     

    This is a fully onsite position in Saint Louis,MO.

     

    Application Deadline

     

    This position is anticipated to close on Oct 8, 2025.

    About Actalent

    Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

     

    The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

     

    If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email [email protected] (%[email protected]) for other accommodation options.