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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly Neuroscience is on the hunt for a passionate associate-level scientist to join our Pain and Neuronal Health discovery biology team. This is your chance to be at the forefront of discovering groundbreaking medicines for brain-related disorders. If you thrive on molecular biological experiments, genetic and genomic assay development, and cutting-edge protein, DNA, RNA, and cloning methods, this role is for you. You'll be instrumental in generating and characterizing Genetically Engineered Model (GEM) lines and conducting cell-based mechanism of action studies to uncover disease-relevant pathways. Your meticulous attention to scientific detail, deep interest in brain pathophysiology, and collaborative spirit will be key to your success.

Are you ready to embark on an exciting research career, contributing to the discovery of new medicines? Are you driven by the desire to improve the lives of patients battling some of the most challenging diseases? Join us and make a difference.

Key Responsibilities:

+ **Collaborate and Innovate:** Work with cross-functional teams in Lilly Research Labs to design and execute high-quality molecular biology studies, advancing our understanding of brain pathophysiology.

+ **Next-Generation Sequencing and Molecular Neuroscience:** Construct NGS libraries and analyze gene/protein expression using advanced techniques like ddPCR, qPCR, RNAseq, RNAscope, Western Blot, ELISA, and MS.

+ **Genetic Material Isolation:** Extract high-quality genetic material from human and mammalian tissues and cells, employing specialized methods such as extrasynaptic vesicle isolations.

+ **In Vitro Experiments:** Perform molecular and genetic experiments, develop cellular models (CRISPR and/or iPSCs), and explore functional genetic variations.

+ **Molecule Screening:** Screen molecules across a variety of biochemical and cell-based assays, including FLIPR, binding, expression, and luciferase readouts.

+ **Research and Collaboration:** Investigate molecular pathways related to neuronal health, collaborating with academic and medical experts to deepen our understanding of neurological diseases.

+ **Data Analysis and Communication:** Utilize your analytical skills and creativity to independently review scientific literature, record, analyze, and communicate data with clear interpretations and proposed next steps.

+ **Problem-Solving:** Demonstrate problem-solving skills and an understanding of inter- and intra-departmental roles for effective coordination of work activities.

Basic Qualifications:

+ Bachelor's Degree in Molecular/Cell Biology or a related scientific field with at least 2-5 years of relevant experience, or a Master's Degree in Molecular/Cell Biology or a related scientific field with scientific research experience.

Additional Skills/Preferences:

+ **Technical Expertise:** Proficiency in nucleotide and protein isolation, NGS library creation, and cloning. Experience with cell culture and common in vitro molecular methods/tools.

+ Experience with rodent necropsies and tissue recovery.

+ **Neuroscience Knowledge:** Experience in neuroscience, psychiatry, and translational biomarkers is preferred but not required.

+ **Communication Skills:** Excellent verbal, written, and presentation skills, with a publication record in peer-reviewed journals.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$63,000 - $162,800

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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