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Job Summary:

SUNY Upstate Research Foundation is seeking a highly motivated Research Scientist to join the Upstate Pharmacology Team and will be responsible for Design Reactions, Synthesis, Purification, and Characterization.

Key Responsibilities:

Design reactions:

+ Conceive, plan, and optimize synthetic routes for novel organic molecules.

+ Apply mechanistic knowledge and structure activity relationships (SAR) to guide reaction design.

+ Evaluate alternative strategies to improve yield, selectivity, scalability, and sustainability.

+ Stay updated on current literature and integrate innovative synthetic methodologies into research.

Synthesis, Purification, and Classification:

+ Carry out multistep organic synthesis with high reproducibility.

+ Perform compound purification using chromatography, crystallization, distillation, or other appropriate methods.

+ Characterize products using NMR, MS, IR, HPLC, GPC, TLC, UVVis, and other analytical techniques.

+ Troubleshoot reactions, analyze side products, and refine conditions for optimal outcomes.

+ Ensure synthesized compounds meet purity, stability, and structural requirements for downstream applications.

Lab Management:

+ Maintain and organize laboratory equipment, chemical inventory, and safety protocols.

+ Train and mentor junior researchers, graduate students, and rotation students in experimental techniques.

+ Ensure compliance with institutional and federal safety regulations (chemical hygiene, waste management, IACUC-related procedures if applicable).

+ Coordinate with collaborators and core facilities for shared instrumentation and services.

+ Support smooth day-to-day laboratory operations, including ordering supplies and scheduling instrument use.

+ Prepare reports and manuscripts:

+ Compile and analyze experimental data into clear figures, tables, and graphs.

+ Write progress reports for principal investigators, funding agencies, or industrial partners.

+ Contribute to drafting and revising manuscripts for peer-reviewed publication.

+ Assist with writing patents, grant applications, or technical documents when needed.

+ Present findings at internal meetings, conferences, and seminars.

Maintain records:

+ Keep accurate, detailed, and timely electronic lab notebooks (ELNs) or paper records of experimental procedures and results.

+ Document experimental parameters, conditions, and troubleshooting notes to ensure reproducibility.

+ Archive and organize analytical data in shared databases for team accessibility.

+ Follow best practices for data integrity, confidentiality, and compliance with institutional policies.

+ Contribute to maintaining transparent workflows that facilitate knowledge transfer across the team.

Minimum Qualifications:

+ PhD in Organic Chemistry or a closely related discipline.

Expertise in chemical synthesis, purification, and characterization.

+ Hands-on experience in chromatography, NMR, MS.

+ Design and execute multistep organic synthesis.

+ Familiar with scale-up synthesis and optimization of synthetic routes.

+ Effective oral and written communication skills.

Preferred Qualifications:

+ Strong record of publications.

+ Ability to work independently and collaboratively.

+ Experience in structure-activity relationship studies and molecule design.

+ Proficiency in handling air- and moisture-sensitive reactions.

+ Experience leading research projects.

Work Days:

Monday - Friday, 9:00 am - 5:00pm

Message to Applicants:

Salary Range: $50,000 - $60,000, DOE

Recruitment Office: Human Resources