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Title Postdoctoral Fellow: Rubin Lab: skeletal muscle project

School Faculty of Arts and Sciences

Department/Area Stem Cell and Regenerative Biology Department

Position Description

A postdoctoral position is open in the Rubin lab, focusing on skeletal muscle regeneration and satellite cell biology.

The Rubin laboratory (https://hscrb.harvard.edu/labs/rubin-lab/) in the Department of Stem Cell and Regenerative Biology at Harvard University is focused on studying complex molecular pathways underlying different disease states, especially late onset neurodegenerative disorders and neuromuscular diseases, with a goal of identifying novel therapeutic avenues. In our skeletal muscle projects, our studies evaluate whether, or not defects in satellite cells may contribute to neuromuscular diseases. Our research combines the use of primary patient-derived cells (iPSCs, myogenic progenitors), genetic mouse models, and phenotypic drug screening methods. In addition, we are examining severe muscle damage that results in a less efficient regenerative process. We use a combination of human and mouse in vivo and in vitro studies to carry out chemical screening and transcriptional profiling analyses to evaluate potential therapeutics related to targeting satellite cells.

A Postdoctoral position is now available for individuals with a background in skeletal muscle regeneration and satellite cell biology. Studies will range from muscle functional assays (quantification of muscle force), isolation and culture of satellite cells, and the mechanistic study of pathways required to confer satellite cell regenerative capacity.

Basic Qualifications

Qualifications:

1. A Ph.D. in satellite cell biology, developmental biology or cell/molecular biology is required. Some familiarity with cell culture, FACS , transcriptional or epigenetic profiling along with mouse husbandry and knowledge of skeletal muscle functional assays is preferred.

2. Demonstrated record of research achievement.

3. Strong written and oral communication skills.

4. Ability to work independently

Additional Qualifications

Interested candidates should submit a cover letter, CV, a brief research proposal, and two to three references’ names and contact information (email, address, telephone number) to Dr. Lee Rubin ([email protected]). Applications will be reviewed on a rolling basis until the position is filled.

Please note: This position is contingent upon funding and satisfactory performance.

Special Instructions

Contact Information

Jane Lalonde

Contact Email [email protected]

Salary Range

67,600—80,000

Pay offered to the selected candidate is dependent on factors such as years of experience, training or qualification, field of scholarship, and accomplishments in the field

Minimum Number of References Required 2

Maximum Number of References Allowed 3

Keywords

EEO/Non-Discrimination Commitment Statement

Harvard University is committed to equal opportunity and non-discrimination. We seek talent from all parts of society and the world, and we strive to ensure everyone at Harvard thrives. Our differences help our community advance Harvard’s academic purposes.

Harvard has an equal employment opportunity (https://hr.harvard.edu/sites/g/files/omnuum6281/files/2025-04/reaffirmation\_statement.pdf) policy that outlines our commitment to prohibiting discrimination on the basis of race, ethnicity, color, national origin, sex, sexual orientation, gender identity, veteran status, religion, disability, or any other characteristic protected by law or identified in the university’s non-discrimination policy (https://provost.harvard.edu/sites/g/files/omnuum3356/files/2025-07/non-discrimination\_and\_anti-bullying\_policies.pdf) . Harvard’s equal employment opportunity policy and non-discrimination policy help all community members participate fully in work and campus life free from harassment and discrimination.

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