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Research Scientist, Cell Biology - Immunology
- Gilead Sciences, Inc. (Foster City, CA)
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We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.
Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.
Job Description
Kite, a Gilead Company, is a biopharmaceutical company focused on the development and commercialization of novel cancer immunotherapy products designed to harness the power of a patient’s own immune system to selectively target and kill cancer cells. Our core technology involves the genetic engineering of T cells, or white blood cells, to express chimeric antigen receptors (CARs) for the treatment of advanced solid and hematological malignancies. We are on a rapid growth trajectory and have a highly energized and accomplished team.
Discovery Research is seeking a highly motivated Research Scientist to lead characterization studies that address product efficacy and safety. The successful candidate will report to a Director and will be expected to independently design and perform experiments, organize and analyze results, and communicate and present findings in team meetings.
DUTIES AND RESPONSIBILITIES** _(include, but not limited to)_ **:
+ Lead assay and study design and implement fit-for-purpose or hypothesis-based experiments for next-generation CAR T products.
+ Provide scientific insights and in-depth data interpretation to inform decision making within the research team and with key stakeholders.
+ Document experimental results to enable future IND and/or patent applications.
+ Collaborate with other scientists to evaluate novel T cell therapies to advance ongoing projects.
+ Work independently with timelines and deliverables in mind.
+ Effectively communicate plans and results in both oral and written form.
+ Utilization of appropriate technology, i.e. Outlook, PowerPoint, FlowJo, Prism and other programs to create and distribute reports and key information.
+ Contribute to a dynamic, exciting culture that embraces teamwork and innovation.
+ Self-motivated, creative, and independent.
+ Positive interpersonal skills with the ability to interact with individuals from a variety of levels and functions.
+ Opportunity to manage and mentor junior scientists in formal and informal settings.
+ Opportunity to present research in cross-functional setting.
Basic Qualifications:
Advanced scientific degree (i.e. MD, PharmD, PhD)
OR
Master’s Degree and 4+ years of scientific experience
OR
Bachelor’s Degree and 6+ years of scientific experience
Preferred** **Qualifications** **:
+ Advanced scientific degree with experience in the following techniques:Tissue culture and sterile technique, Primary immune cell culture, Immunoassays, Multi-color flow cytometry, and Cell proliferation assays.
+ Experience in exploring disease biology with a focus on solid tumors.
+ Strong background in cancer immunotherapy, human immunology, and/or gene therapy.
+ Capable of high-performance work in independent and team settings.
+ Experience working with engineered T cells and/or other immune cell types (i.e., NK cells, myeloid cells, etc.).
+ Direct experience in cell engineering using viral or non-viral methods or gene editing.
+ Understanding of protein engineering and synthetic biology principles applied to cell therapy .
+ Demonstrated independence in experimental design, data analysis, interpretation, and presentation.
+ Experience in T-cell functional characterization assays including _in vitro_ cytotoxicity, proliferation, cytokine/chemokine measurements, cell signaling, activation, differentiation, and exhaustion.
+ Proficient in cell culture aseptic technique.
+ Proficient in multi-parameter flow cytometry (panel design, sample acquisition, data processing) and data analysis (FACSDiva, FlowJo, GraphPad Prism, Excel).
+ Maintain a high degree of accuracy and attention to detail; strong organizational and record keeping skills.
+ Maintain a high degree of ethical standards and trustworthiness.
+ Ability to think and adapt to a rapidly changing environment and demands.
+ Able to reach rational conclusions through processing of complex information.
+ Promotes innovation through creative solutions.
+ Energized by accomplishments and excellence in the workplace.
+ Excellent time management skills.
The salary range for this position is: $146,540.00 - $189,640.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
https://www.gilead.com/careers/compensation-benefits-and-wellbeing
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com . Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma .
For jobs in the United States:
Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact [email protected] for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' (https://www.eeoc.gov/employers/eeo-law-poster) poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT (http://www.dol.gov/whd/regs/compliance/posters/eppac.pdf)
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
Kite Pharma will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Kite Pharma Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday.
Change The World With Us
Everyone at Kite is grounded by one common goal – curing cancer. Every day, we aim to establish a direct line between that purpose and our day-to-day work.
We are creating Kite together, with the recognition that the best teams are built by the best people. We maintain an attitude of curiosity, and creativity with each challenge as we develop a new market for cancer therapies. We appreciate and respect one another, and most importantly, we don’t take success for granted.
While we’ve come a long way to make what others viewed as impossible, possible, we know one thing is certain. Today is just the beginning.
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Research Scientist, Cell Biology - Immunology
- Gilead Sciences, Inc. (Foster City, CA)