• Biologist

    System One (Boston, MA)


    Job Title: Biologist

    Work schedule: Mon - Fri 8AM - 5PM

    Pay Range: $40 - $45.40/hr

     

    Type: Contract, Potential for extension or conversion to permanent

    Requirements

    Qualifications

    + Education: Master’s degree in Biochemistry, Chemical Engineering, Biotechnology, or related field.

    + Experience: Minimum 2 years of hands-on purification experience in an academic or industry setting.

    Technical Skills

    + Strong knowledge and practical experience with ion-exchange and affinity chromatography.

    + Familiarity with buffer preparation.

    + Understanding of basic analytical methods for product characterization.

    Preferred Qualifications

    + Experience in AAV or other viral vector purification.

    + Experience with AKTA systems and Unicorn software.

    Responsibilities

    We are seeking a highly motivated Contractor – Purification Scientist to join our Downstream Process Development team. The successful candidate will contribute to the purification and characterization of viral vectors, biologics, or recombinant proteins to support process development and manufacturing activities. The ideal candidate has hands-on experience in ion-exchange chromatography, affinity purification, and tangential flow filtration (TFF), with a strong understanding of purification principles and data analysis.

    Key Responsibilities

    • Execute purification processes including affinity chromatography (e.g., AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and other polishing steps.

    • Operate AKTA systems (Avant, Pure, or Pilot) for small- to large-scale purification runs.

    • Perform TFF operations for buffer exchange and concentration of intermediate or final products.

    • Support experimental design, data collection, and documentation following established procedures and GMP/GLP best practices.

    • Assist in troubleshooting and optimization of purification processes.

    • Analyze in-process and purified samples using relevant analytical methods (e.g., UV, SDS-PAGE, ddPCR, ELISA, or HPLC).

    • Collaborate cross-functionally with upstream, analytical, and manufacturing teams.

    • Maintain lab equipment, manage buffers and column inventory, and ensure compliance with safety and documentation standards.

     

    Benefits

     

    System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

     

    Ref: #558-Scientific

     

    System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

     

    System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.