• Post-Doctoral Fellow in Lung Biology

    University of Pennsylvania (PA)


    Mentor: Michael F. Beers MD

     

    Department: Pulmonary and Critical Care Medicine

     

    Funding Sources: NIH, Departmnt of Veterans Affairs, and Endowment

     

    Open to US Citizens and Forign Nationals

     

    The Lung Epithelial Biology Laboratory at the Penn Lung Biology Institute (LBI), under the direction of Dr. Michael Beers, has an exceptional opportunity available for Postdoctoral Fellows to join a collaborative research project directed at unraveling the mysteries of idiopathic pulmonary fibrosis and other parenchytmal lung diseases.

     

    The Beers’ Lab has an existing program funded by NIH, the Department of Veterans Affairs, private foundations, and industry to study the molecular mechanisms that regulate tissue injury and repair in focused on discovery, target ID, target validation, and proof or principal studies aimed at uncovering and exploiting novel pathways to treat fibrotic lung diseases. The postdoctoral fellow can focus the project in any of several related areas (epithelial biology, immunological networks, metabolomics, epithelial-mesenchymal crosstalk, and/or transcriptomics/proteomics) using 2 novel published models of lung injury and fibrosis (see https://www.ncbi.nlm.nih.gov/pubmed/29920187; https://www.ncbi.nlm.nih.gov/pubmed/30910861; https://www.ncbi.nlm.nih.gov/pubmed/30721158 . In addition to the unique mouse reagents, the successful candidate will have access to a variety of cutting edge technologies including RNAseq, single cell and ATAC RNAseq, high resolution proteomics, CRISPR mediated screens, lineage tracing, organoid assays, and iPS cells to identify pathways critical for lung tissue repair and regeneration. The ideal candidate will have an M.D., Ph.D. or MD/PhD with a strong background in basic molecular and cell biology skills. Experience utilizing mouse models and primary cell culture systems is required for the success of this position.

     

    Qualifications and Requirements

     

    + PhD in Cell Biology, Biochemistry, Immunology, or related Biomedical Fields

    + Solid background in molecular biology, biochemistry, genetics and cell biology

    + Hands-on experience with animal models, mammalian tissue culture, molecular biology techniques and tissue imaging procedures are required

    + Excellent record of publications in highly respected international scientific journals

    + Familiarity with advanced imaging techniques, transcriptomic profiling, flow cytometry, and/or bioinformatics is desirable

     

    To apply for this position, applications should also be uploaded in Ineterfolio with the link Provided

     

    In addition please email [email protected] with subject line Postdoctoral Fellow Lung Biology with the following items attached:

     

    + Current CV

    + Cover letter

     

    The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.