• Research Scientist- CryoEM Facility

    Massachusetts Institute of Technology (Cambridge, MA)


    Research Scientist- CryoEM Facility

     

    + Job Number: 25269

    + Functional Area: Research - Scientific

    + Department: Biology

    + School Area: Science

    + Pay Range Minimum: $73,000

    + Pay Range Maximum: $111,000

    + Employment Type: Full-Time

    + Employment Category: Exempt

    + Visa Sponsorship Available: No

    + Schedule:

    + Pay Grade: No Grade

     

    Email a Friend Save Save Apply Now

    Posting Description

    RESEARCH SCIENTIST, CRYOEM FACILITY, Biology, will be supporting a diverse and expanding research community in cryogenic sample preparation, imaging, and data analysis and will train and support users in specimen preparation, data collection, and cryoEM/cryoET workflows; maintain and calibrate instruments; assist in collaborative projects; and help shape next-generation techniques in structural biology including leading the integration of the HydraBio system for advanced in situ studies using fluorescence-guided targeting. Located within MIT.nano, the facility features cutting-edge instrumentation, including a Titan Krios (BioQuantum-K3), Talos Arctica (Falcon3EC/K3), and an Aquilos cryo-FIB/SEM (soon to be upgraded to a HydraBio plasma FIB/SEM with Delmic METEOR fluorescence microscope), along with Chameleon and Vitrobot vitrification systems and robust computational infrastructure. Responsibilities include user training and mentoring (~35%), facility operations and administration (~30%), collaborative work and staff-assisted usage (~20%), equipment maintenance (~10%), and community engagement (~5%).

     

    Full job description available here: https://acrobat.adobe.com/id/urn:aaid:sc:US:f059be7d-5ede-4b97-bc69-8e9534a9f699

    Job Requirements

    REQUIRED: Ph.D. in biochemistry, structural biology, biophysics, or a related discipline; demonstrated expertise in transmission electron microscopy (TEM) and/or scanning electron microscopy (SEM); familiarity with cryogenic sample preparation methods; strong troubleshooting, organizational, and interpersonal skills; ability to work independently while balancing the needs of a multi-user facility; and commitment to training and supporting a diverse scientific community. PREFERRED: Four+ years of research experience in biological electron microscopy; experience with cryo-FIB milling and lamella preparation; background in SPA, cryo-electron tomography, or related data processing workflows; experience identifying and diagnosing microscope or equipment performance issues; proficiency with computational tools for cryoEM data analysis; experience with Python, Linux, or HPC environments; and experience in a multi-user or shared research facility.

     

    10/20/2025