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Research Scientist/Engr 3
- University of Washington (Seattle, WA)
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Job Description
Field of research:
Applied biomedical research in the PI’s lab with emphasis on spatial omics assays—e.g., translational spatial genomics, imaging‑based profiling, assay/methods development, computational analysis. Work spans study design, method optimization, data analysis, and manuscript preparation supporting sponsor deliverables.
Purpose of Research:
Execute and advance funded specific aims across multiple awards; develop/optimize protocols and analysis pipelines; integrate datasets across projects; lead publications (two manuscripts currently in preparation); and mentor trainees to ensure continuity and scale.
Duties and Responsibilities:
Lead research & methods development — design experiments/analyses; develop/validate protocols; ensure data quality & reproducibility (50%).
Project & data management — coordinate cross‑project timelines/milestones; maintain code/data pipelines; ensure documentation & compliance (20%).
Publications & dissemination — lead/manuscript writing (two in prep), figure generation, conference abstracts/talks, responses to peer review (15%).
Training & mentorship — guide graduate students/staff in techniques, analysis, and best practices; promote safety and rigor (10%).
Lab/administrative support — compliance, inventories, purchasing coordination, and core/fee‑for‑service interactions (5%).
Requirements:
Bachelor's Degree in Biochemistry, Molecular biology, genetics, bioinformatics and 4 years of relevant experience relevant experience in the lab’s primary methods such as molecular biology, next gen sequencing and quantitative data analysis in Python/R.
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Equivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.
ADDITIONAL REQUIREMENTS
1. Spatial transcriptomics assay setup & optimization: tissue cryosectioning/fixation, array/barcode handling, multi‑cycle hybridization.
2. DNA‑barcoded immunolabeling (antibodies/oligo‑tags): titration, controls, panel QC.
NGS library prep & run QC: UMI/barcode handling, cleanup/indexing, Qubit/Bioanalyzer, pass/fail metrics.
3. Imaging & decoding: slide‑scanning fluorescence, cycle registration/drift correction, mapping to pixel coordinates.
4. Primary processing & first‑pass analysis: demux/trim/align to pixel‑level count matrices; QC metrics & basic clustering/plots; Python or R; SOP/ELN.
Desire:
1. Experience with spatial and single-cell multiomics.
2. Barcode design/error‑aware decoding; ambient/background correction.
3. Segmentation & deconvolution (e.g., Cellpose/Scanpy/Seurat or similar).
4. Workflow/HPC (Snakemake/Nextflow, containers) and data management (e.g., S3/Globus).
5. Basic instrument/automation scripting (e.g., Micro‑Manager); publications, grants, mentoring.
CONDITIONS OF EMPLOYMENT
This position is eligible for H1-B visa sponsorship.
Compensation, Benefits and Position Details
Pay Range Minimum:
$72,288.00 annual
Pay Range Maximum:
$82,500.00 annual
Other Compensation:
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Benefits:
For information about benefits for this position, visit https://www.washington.edu/jobs/benefits-for-uw-staff/
Shift:
First Shift (United States of America)
Temporary or Regular?
This is a regular position
FTE (Full-Time Equivalent):
100.00%
Union/Bargaining Unit:
UAW Research
About the UW
Working at the University of Washington provides a unique opportunity to change lives – on our campuses, in our state and around the world.
UW employees bring their boundless energy, creative problem-solving skills and dedication to building stronger minds and a healthier world. In return, they enjoy outstanding benefits, opportunities for professional growth and the chance to work in an environment known for its diversity, intellectual excitement, artistic pursuits and natural beauty.
Our Commitment
The University of Washington is proud to be an affirmative action and equal opportunity employer (https://hr.uw.edu/eoaa/) . All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or [email protected] .
Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law (https://app.leg.wa.gov/RCW/default.aspx?cite=28B.112.080) .
University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.
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