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Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok (https://www.tiktok.com/@abbvie) .

Job Description

We are seeking a Senior Scientist II with a background in molecular biology and/or microbiology to join our peptide display hit generation team. In this role, you will:

+ Lead and manage technology development projects and therapeutic peptide hit generation efforts.

+ Utilize phage-display and/or mRNA-display peptide technologies, including the design and generation of peptide display libraries, screening against therapeutic targets, and identification and maturation of pharmaceutically relevant hits.

+ Drive internal hit generation initiatives and manage relationships with contract research organizations (CROs) to achieve project goals.

+ Leverage our innovative peptide microarray platform to accelerate hit identification and maturation from peptide display campaigns.

This position offers the opportunity to play a key role in discovering impactful peptide therapeutics within a collaborative and innovative team.

Responsibilities:

+ Lead the development of in-house peptide display workflows utilizing our proprietary peptide microarray platform to accelerate hit identification. Responsibilities include designing and generating display libraries, screening peptide libraries against therapeutic targets, performing next-generation sequencing, and conducting large-scale data analysis.

+ Explore and assess advanced technologies for modifying peptide display libraries, such as chemical modification and incorporation of non-canonical amino acids.

+ Use proprietary data analysis tools to efficiently analyze next-generation sequencing data and other large-scale datasets derived from peptide display libraries.

+ Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.

+ Publish research in peer-reviewed journals and present work at scientific conferences.

+ Seize opportunities to pursue project relevant leads that are in line with the group’s strategy.

+ Demonstrates high proficiency across a wide range of relevant technologies.

+ Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.

+ Primary author of publications, presentations, regulatory documents and/or primary inventor of patents.

+ Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials

+ May mentor/supervise a team of one or more and guide and evaluate the performance of those individuals.

Qualifications

Required:

+ Bachelor’s Degree or equivalent education and typically, 12 years of experience, Master’s Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience. Degree(s) should be in Molecular Biology, Microbiology, Biochemistry, Chemical and Biological Engineering, or other relevant fields.

+ Experience with mRNA-display and/or phage-display libraries, including the design and generation of libraries, screening processes, and subsequent data analysis.

+ Proficiency in generating next-generation sequencing (NGS) libraries and analyzing the resulting sequencing datasets.

+ Coding skills relevant to data science (e.g., Python) or a demonstrated willingness to learn such skills.

+ Demonstrated ability to learn, understand and master new experimental techniques.

+ Ability to multitask and work within timelines.

+ Effective writer and communicator of research

Preferred:

+ Experience with automation and/or molecular barcoding for scaling molecular biology/microbiology workflows

+ Experience managing other researchers/technicians or with managing relationships with contract research organizations

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

+ The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

+ We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

+ This job is eligible to participate in our short-term incentive programs. ​

+ This job is eligible to participate in our long-term incentive programs​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Salary: $106,500 - $202,500