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The Position

A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Domagoj Vucic in the Department of Immunology Discovery at Genentech. Vucic lab works on inflammatory signaling pathways with the aim of identifying novel targets in the field of inflammatory diseases. This position will focus on TNF family signaling, particularly on TNF (Tumor Necrosis Factor) and TL1A (TNF-like ligand 1A). Several anti-TL1A antibodies have shown remarkable efficacy in Inflammatory Bowel Disease (IBD) clinical trials but mechanistic details of TL1A mediated signaling are not fully understood. This postdoctoral position will provide an opportunity to contribute to target discovery and mechanistic examination of TL1A and TNF regulated pathways using in vitro and in vivo experiments related to molecular, cellular and inflammatory biology. Candidates familiar with TNF family signaling and innate immunity are especially encouraged to apply.

The Opportunity:

+ You will have opportunities to productively collaborate with other researchers across departments, present your work to project teams, and contribute to scientific publications.

+ As a member of the Immunology Discovery Department, you will join leaders in identifying molecular causes and targets for immune-inflammatory diseases

+ You will be part of the Genentech post-doctoral training program that provides an outstanding environment and the opportunity to pursue fundamental basic science questions in an environment focused on drug development and breakthrough discoveries.

Who You Are:

+ Ph.D. with a proven track record of excellence in cellular/ molecular biology and/or immunology

+ Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal.

+ Independent scientist with outstanding communication skills, a strong passion and commitment to science and inflammatory signaling, who works well within a team

+ Excited about identifying novel targets for treatments of inflammatory diseases

Preferred Qualifications:

+ Hands-on experience in inflammatory signaling studies is highly desired

+ Track record of successfully conducting laboratory experiments

+ Working knowledge of biochemical techniques is a plus.

For information about the Vucic lab at Genentech, please go to:

https://www.gene.com/scientists/our-scientists/domagoj-vucic

https://pubmed.ncbi.nlm.nih.gov/?term=vucic+d+genentech&sort=date

The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.

Benefits (https://roche.ehr.com/default.ashx?CLASSNAME=splash)

Relocation benefits are available for this job posting.

Postdoc Program

Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.

The Genentech Postdoc Program (http://careers.gene.com/us/en/students-postdocs) provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (https://docs.google.com/forms/d/e/1FAIpQLSdZWlsbfQOvFVIQgHE\_iDzWUTlhZvj6FytIzjS7xq6IGh1H5g/viewform) .