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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub** **Function:

Translational Discovery & Development Biomarkers

Job Category:

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Translational Sciences and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Sciences (TS) team which uses human based data and tissues to support the end to end portfolio. Together, the TSM group will provide the key learnings/insights on the next wave of novel therapies for these patients. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases.

TS has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision- making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. It has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development.

This position will reside within the Immunology Translational Sciences department and requires a highly motivated and skilled candidate to lead clinical biomarker assay development across Respiratory diseases.

Respiratory Translational Sciences team leads the development of innovative therapies for respiratory immune-mediated diseases such as asthma, COPD, and other T2 and non-T2 inflammatory conditions.

We are searching for the best talent for a Senior Scientist. This role is an individual contributor position where the desired candidate will ideally be a developing subject matter expert, who works independently with minimal supervision. Contributes to assay development in the lab, completes documentation associated with laboratory work, and trains and reviews the work of other laboratory members. Identifies solutions to problems pertaining to laboratory work and processes and implements them. Recent lab-based experience in T2 and non-T2 immune cell analysis and patient sample analysis relevant to asthma and COPD (e.g. sputum) is highly relevant. The successful candidate will utilize a full suite of advanced technologies to enable cutting edge research and key activities will include leading biomarker discovery efforts, assay development/validation, respiratory indication sample analysis

Your role will be to:

+ Lead clinical biomarker assay development and execution using flow cytometry, ELISAs and other similar immunoassay platforms, RNA/DNA purification, qPCR, and/or tissue culture

+ Design and execute experiments to discover new biomarkers and/or assays for portfolio assets

+ Analyze data and communicate results to project team in a timely manner

+ Partner with external partners as needed to support Immunology portfolio programs

+ Work closely with other lab-based personnel to ensure optimal laboratory environment (collaboration, culture, safety, etc.)

+ Work independently and manage multiple projects simultaneously under fixed timelines

+ Contribute to the preparation of and submission of technical reports, prepare clear and concise summaries, and present to project teams and colleagues

+ Take initiative to identify, pilot and internalize emerging technical approaches that may drive increased value for portfolio execution

+ Deliver on study milestones and commitments and foster a collaborative, creative, and rigorous culture of scientific discovery

+ Coach and train junior colleagues in techniques, processes, and responsibilities.

+ Integrate Johnson & Johnson’s Credo and Leadership Imperatives into team goals and decision-making.

Qualifications / Requirements:

+ B.A./B.S. with 7+ years related experience OR M.S. with 6+ years research experience OR PhD with 0-2+ years research experience (academic or industry) is required

+ Experience in translational research in an industry setting is strongly preferred, including biomarker assay development and validation and clinical sample analysis

+ Experience with soluble assays and protein profiling, in vitro and ex vivo assays with immune cells is strongly preferred

+ Experience gaining biological insights using translational and biomarker high dimensional biological data (e.g., flow cytometry, proteomics, transcriptomics) is preferred

+ Self-motivated, creative, and focused; able to work within a team and to collaborate with colleagues to achieve program goals.

+ Attention to detail

+ Comfort in ambiguity and flexibility to meet the growing needs of the team and portfolio

+ Intellectual curiosity and excitement to learn new techniques and technologies.

Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company’s long-term incentive program.

Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits:

Vacation –120 hours per calendar year

Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year

Holiday pay, including Floating Holidays –13 days per calendar year

Work, Personal and Family Time - up to 40 hours per calendar year

Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child

Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member

Caregiver Leave – 10 days

Volunteer Leave – 4 days

Military Spouse Time-Off – 80 hours

Additional information can be found through the link below.

https://www.careers.jnj.com/employee-benefits

The anticipated base pay range for this position is: $104,000 - $166,750

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.

\#LI-Hybrid

Required Skills:

Assay Validation, Biomarker Analysis, Biomarker Assay Development, Biomarker Development, ELISA Techniques

Preferred Skills:

Biomarkers, Translational Research

The anticipated base pay range for this position is :

Additional Description for Pay Transparency: