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The laboratory of Dr. Milena Kordalewska is seeking an experienced and highly motivated **Senior Research Specialist, Antifungal Drug Development** to take a leading experimental role in our translational research programs focused on the development of novel antifungal drugs. Our lab is at the forefront of investigating emerging and drug-resistant fungal pathogens, and this senior position offers a unique opportunity to significantly contribute to a collaborative, mission-driven team. The successful candidate will be instrumental in driving preclinical drug discovery initiatives, with the ultimate goal of addressing a significant global health threat and improving patient outcomes.

Key responsibilities will include:

+ Independently design, execute, and troubleshoot complex experiments that are foundational to our drug development pipeline.

+ Lead the implementation of comprehensive _in vitro_ evaluations to determine the potency and spectrum of activity of novel antifungal compounds.

+ Develop and optimize a variety of molecular biology assays to elucidate mechanisms of drug action and resistance.

+ Optimize and execute _in vivo_ drug efficacy models in rodents to assess the therapeutic potential of lead candidates.

We are seeking a candidate with substantial experience in microbiology, pharmacology, or a related field, coupled with a proven track record in translational research. The following lab experience and skills are highly desirable:

+ Extensive hands-on expertise in cultures of microbial pathogens, particularly yeasts and filamentous fungi.

+ Demonstrated proficiency in a wide range of drug susceptibility testing methodologies.

+ Proven experience with _in vitro_ and _in vivo_ biofilm models.

+ Strong background in molecular biology techniques, e.g., PCR, nucleic acid isolation.

+ Experience with animal models of infectious diseases, including drug administration, tissue collection, and data analysis.

The **Center for Discovery and Innovation- CDI** was established by **Hackensack Meridian** **_Health_** **(HMH)** as an academic basic and translational research enterprise to rapidly translate science innovation to the clinic and to improve outcomes for patients with cancer, infectious diseases, autoimmune disease and other acute and chronic diseases. The CDI has grown rapidly since its origins in 2019, and now has 39 labs, 200+ scientists and allied personnel supported by 78 NIH and DoD grants and more than 87 other grants and contracts. Areas of expertise include genomics, epigenetics, drug resistance, stem cell biology, drug discovery, diagnostics and biomarker development, rheumatology and pharmacology.

**Education, Knowledge, Skills and Abilities Required** :

+ Bachelor's diploma/degree in lab specific field or other relevant area of study.

+ Minimum of 4 or more years of experience.

+ Meticulous record keeping to ensure integrity of the data.

+ Must be able to work independently and have a strong work ethic.

+ Lab specific technical skills.

+ Excellent written and verbal communication skills.

+ Proficient computer skills that include but are not limited to Microsoft Office and/or Google Suite platforms.

+ Must be flexible in work schedule. Must be available to occasionally come to the laboratory on a weekend day for a few hours or stay late in evenings for a given experiment.

**Education, Knowledge, Skills and Abilities Preferred** :

+ Recent Ph.D. (within 2 years) or Master's degree.

+ Experience working in a BSL2/BSL3 lab facility.

+ Experience with small animal handling.

+ Previous experience in lab specific field.

+ Other lab specific.

If you feel that the above description speaks directly to your strengths and capabilities, then please apply today!

173275

Minimum rate of $49,857.60 Annually

HMH is committed to pay equity and transparency for our team members. The posted rate of pay in this job posting is a reasonable good faith estimate of the minimum base pay for this role at the time of posting in accordance with the New Jersey Pay Transparency Act and does not reflect the full value of our market-competitive total rewards package.

The starting rate of pay is provided for informational purposes only and is not a guarantee of a specific offer. Posted hourly rates may be stated as an annual salary in the offer and posted annual salaries may be stated as an hourly rate in the offer, depending on the level and nature of the job duties and credentials of the candidate. The base compensation determined at the time of the offer may be different than the posted rate of pay based on a number of non-discriminatory factors, including but not limited to:

+ Labor Market Data: Compensation is benchmarked against market data to ensure competitiveness.

+ Experience: Years of relevant work experience.

+ Education and Certifications: Level of education attained, including specialized certifications, credentials, completed apprenticeship programs or advanced training.

+ Skills: Demonstrated proficiency in relevant skills and competencies.

+ Geographic Location: Cost of living and market rates for the specific location.

+ Internal Equity: Compensation is determined in a manner consistent with compensation ranges for similar roles within the organization.

+ Budget and Grant Funding: Departmental budgets and any grant funding associated with the job position may impact the pay that can be offered.

Some jobs may also be eligible for performance-based incentives, bonuses, or commissions not reflected in the starting rate. Certain positions may also be eligible for shift differentials for work performed on evening, night, or weekend shifts.

In addition to our compensation for full-time and part-time (20+ hours/week) job positions, HMH offers a comprehensive benefits package, including health, dental, vision, paid leave, tuition reimbursement, and retirement benefits.

HACKENSACK MERIDIAN HEALTH (HMH) IS AN EQUAL OPPORTUNITY EMPLOYER

All qualified applicants will receive consideration for employment without regard to age, race, color, creed, religion, sex, sexual orientation, gender identity or expression, pregnancy, breastfeeding, genetic information, refusal to submit to a genetic test or make available to an employer the results of a genetic test, atypical hereditary cellular or blood trait, national origin, nationality, ancestry, disability, marital status, liability for military service, or status as a protected veteran.