• Research Associate

    University of North Carolina- Chapel Hill (Chapel Hill, NC)


    Employment Type: Permanent Staff (EHRA NF)

     

    Vacancy ID: NF0009410

     

    Salary Range: $65,000 - $70,000

    Position Summary/Description:

    The Research Associate will research the mechanisms of innate immune responses in the lungs to stimuli, including bacteria and tobacco smoke. The goal of these studies will be to understand the effect of bacterial and viral pathogens on the lungs and how the lungs protect themselves and other organs against these stimuli.

    Education and Experience:

    Preferred qualifications include:

    * Completion of a post-doctoral fellowship in lung pathobiology.

    * Experience in Higher Education or University setting.

    * Relevant publication & documenting expertise.

    * Knowledge of leukocyte kinetics, particularly neutrophils, macrophage subpopulations and NK cells, is important.

    * Expertise and a minimum of 3 years experience in:

     

    1) Mouse models of lung disease, especially pneumonia and acute lung injury, including multi-parameter phenotyping of protein expression, leukocyte kinetics, cell function, lung physiology and bacterial clearance;

     

    2) 3-laser flow cytometry of single cell digests of lungs and other organs using complex multi-fluorochrome labeling of multiple immune cell populations and functional activities and analysis of flow cytometric data, including experience with CytExpert and use of publicly accessible databases;

     

    3) RNA isolation and quality evaluation, real time PCR , gene transcription profiling using gene and microRNA arrays of whole tissue and individual cell types, and bioinformatic analyses using at a minimum the GSEA , Cytoscape, DAVID Bioinformatics Resources and the Lung Cell Atlas.

    Essential Skills:

    Experience in writing manuscripts and grants is required. Must also possess strong organizational skills, as well as the ability to communicate effectively and work on multiple projects simultaneously.

    AA/EEO Statement:

    The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.