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Life Science Research Professional 1 (On-Site Only)

School of Humanities and Sciences, Stanford, California, United States

New

Research

Post Date 3 days ago

Requisition # 107816

_This position has been deemed critical by the School of Humanities & Sciences Dean's Office and is exempt from the hiring freeze._

Life Science Research Professional 1 (On-Site Only)

TheSchool of Humanities and Sciences (H&S)is the foundation of a liberal arts education at Stanford. The school encompasses 24 departments and 24 interdisciplinary programs. H&S is home to fundamental and applied research, where free, open, and critical inquiry is pursued across disciplines. As the university’s largest school, H&S serves as the foundation of a Stanford undergraduate education no matter which discipline students pursue as a major. Graduate students work alongside world-renowned faculty to pursue and shape foundational research that leads to breakthroughs and discoveries that shed new light on the past, influence the present, and shape the future. Together, faculty and students in H&S engage in inspirational teaching, learning, and research every day.

DEPARTMENT DESCRIPTION:

The Department of Biology at Stanford University is devoted to discovering fundamental knowledge of the living world: from the behavior of single molecules to dynamics of cells, organisms, populations, and interactions of biological systems with our planet. We are dedicated to developing innovative training experiences for the next generation of biologists, and to building an inclusive learning environment that unites scientists from diverse disciplines and life experiences to creatively address critical questions for today’s world. Learn more athttps://biology.stanford.edu/

POSITION SUMMARY:

The Yan Lab at Stanford Biology is actively searching for intellectually motivated and self-driven post-bacc trainees from a **broad academic background** (including biology, chemistry, physics, engineering, and relevant fields) to assemble a **collaborative** team of talent with complementing expertise and, most importantly, **eager to learn and pursue new and challenging lines of research** dedicated to advance our knowledge in cellular mechanics and force dynamics.

To study cellular mechanics _in situ_ , currently we are developing new genetically encoded force sensors and tension gauges and constructing novel imaging platform _ad hoc_ to directly visualize these hidden physical parameters present inside and exerted by the cells. We will use optical tweezers to calibrate each molecular probe and identify constructs with proper dynamic ranges for probing cellular forces and tensions. The precise magnitude and dynamic coordination of these physical parameters are key to _discern how cells interpret and integrate mechanical cues both from within and among interfacing neighbors_ , which is the core of our lab’s research.

In the lab, you will work closely with other lab members as well as the principal investigator and be heavily involved in the planning, execution, and publication of exciting science. In general, the day-to-day work in the position will focus on the design and cloning (construction and validation of plasmids) of the genetically encoded molecular probes, culture and construction of mammalian cell lines, as well as conducting experiments and data analysis. In addition, there will be the opportunity to learn and apply powerful high-resolution imaging and state-of-the art biophysical techniques such as spinning disk confocal fluorescence microscopy and adaptive optical tweezers. A small amount of time will be devoted to lab organization/safety. Overall, this is an excellent opportunity for anyone with an undergraduate or master degree and previous experience with molecular/cellular biology techniques. Familiarity with mammalian stem cell culture or CRISPR-based approaches is a plus but is not required.

We are fully committed to helping all lab members accomplish their professional goals by developing skills sought after in both academia and industry, providing recommendation letters, and helping to craft compelling applications. We especially encourage people from backgrounds historically underrepresented in science to apply. We are a group of _gap seekers_ and _bridge builders,_ and we hope you will join us to unravel the long hidden mechanical dimension in biology.

This is a 100% FTE, 1-year fixed term, non-exempt position with a possible renewal. This position will be based on the Stanford campus.

If you believe that this opportunity is a match for your knowledge, skills and abilities, we encourage you to apply. Thank you for considering employment opportunities with the School of Humanities and Sciences.

CORE DUTIES:

+ Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.

+ Independently conduct experiments; maintain detailed records of experiments and outcomes.

+ Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.

+ Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.

+ Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.

+ Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.

+ Assist with orientation and training of new staff or students on lab procedures or techniques.

* Other duties may also be assigned.

EDUCATION AND EXPERIENCE:

+ Bachelor's degree in related scientific field.

KNOWLEDGE, SKILLS, AND ABILITIES:

+ General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.

+ Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.

+ Ability to maintain detailed records of experiments and outcomes.

+ General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.

+ Ability to work under deadlines with general guidance.

+ Excellent organizational skills and demonstrated ability to accurately complete detailed work.

In addition, preferred requirements include:

**1. Highly self-driven, scientifically rigorous, and strong training/extensive experience in a subset (** **_not all_** **) of the following** :

a. Molecular and cellular biology – molecular cloning; transcription and translation; cell culture and cell line constructs (e.g., embryonic stem cells, mammalian and insect cells), aseptic techniques and cell transfections; FACS; WB/IP/ChIP analysis

b. Biochemistry – protein folding, engineering and purification; molecular sensor and probe design; functional assay development; DNA and RNA template design and synthesis

c. Microscopy and instrumentation – optics, optical trapping, iSCAT, confocal and fluorescence imaging, microfluidics

d. Scripting, programing, coding – MATLAB, LabVIEW, Fiji/ImageJ, Python, and/or R for statistical analysis and image analysis

2. Proactive problem-solving skills; ability to work independently and to take appropriate autonomous initiative to carry out research work.

3. Agile, adaptive, and accountable as a researcher and a team member; organized and diligent at documentation; outstanding ethics in handling scientific data and results.

WORKING CONDITIONS:

+ May require working in close proximity to blood borne pathogens.

+ May require work in an environment where animals are used for teaching and research.

+ Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.

+ Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.

+ May require extended or unusual work hours based on research requirements and business needs.

The expected pay range for this position is $32.58 to $38.48 per hour.

Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.

At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.

Why Stanford is for You

Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with:

+ **Freedom to grow** . We offer career development programs, tuition reimbursement, or audit a course. Join a film screening, or listen to a renowned author or global leader speak.

+ **A caring culture** . We provide superb retirement plans, generous time-off, and family care resources.

+ **A healthier you.** Climb our rock wall, or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.

+ **Discovery and fun.** Stroll through historic sculptures, trails, and museums.

+ **Enviable resources** . Enjoy free commuter programs, ridesharing incentives, discounts and more.

_The job duties listed are typical examples of work performed by positions in this job classifications and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned._

_Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants_

_requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources at [email protected]. For all other inquiries, please submit a_ _contact form_ _._

_Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law._

Additional Information

+ **Schedule: Full-time**

+ **Job Code: 4943**

+ **Employee Status: Fixed-Term**

+ **Grade: E**

+ **Requisition ID: 107816**

+ **Work Arrangement : On Site**