• Research Fellow

    University of Michigan (Ann Arbor, MI)


    RESEARCH FELLOW

    Job Summary

    This project will involve generating and testing brain-penetrant antibody-nucleic acid conjugates for reducing gene expression in the brain after intravenous administration. The goal is to prevent pathology in mouse models of neurodegenerative disease using a noninvasive, antibody-based technology.

    Responsibilities*

    The responsibilities will include cloning and producing bispecific antibodies, conjugating nucleic acids, and testing their pharmacokinetics and pharmacodynamics in vivo. In addition, the duties will also include testing the ability of the antibody-nucleic acid conjugates to prevent pathology in mouse models of neurodegenerative diseases.

    Required Qualifications*

    Molecular biology cloning of proteins and/or antibodies, protein expression and purification, and some animal handling experience.

    Desired Qualifications*

    Experience performing pharmacokinetic analysis of antibody or other protein therapeutics.

     

    Modes of Work

     

    Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about thework modes (https://hr.umich.edu/working-u-m/my-employment/ways-we-work-resource-center/ways-we-work-implementation-group/modes-work) .

     

    Background Screening

     

    The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.

     

    U-M EEO Statement

     

    The University of Michigan is an equal employment opportunity employer.

     

    Job Detail

     

    Job Opening ID

     

    271435

     

    Working Title

    RESEARCH FELLOW

    Job Title

    RESEARCH FELLOW

    Work Location

     

    Ann Arbor Campus

     

    Ann Arbor, MI

     

    Modes of Work

     

    Onsite

     

    Full/Part Time

     

    Full-Time

     

    Regular/Temporary

     

    Regular

     

    FLSA Status

     

    Exempt

     

    Organizational Group

     

    College Pharmacy

     

    Department

     

    PHARMACY Pharmaceutical Sci

     

    Posting Begin/End Date

     

    12/01/2025 - 2/01/2026

     

    Career Interest

     

    Research Fellows