• Scientist I

    Adecco US, Inc. (Framingham, MA)


    **Adecco Healthcare & Life Sciences** is hiring a highly motivated **Molecular Biology Scientist** on behalf of a leading global biopharmaceutical partner in Framingham, MA.

    **Pay:** Up to **57.95/hr** based on education and relevant experience level

     

    Duration: 1 year Contract to Hire

     

    This role will join a high-performing, collaborative Cell Line Development team focused on advancing CHO cell line development platforms through modern molecular biology techniques and automation.

     

    The scientist will contribute to the optimization of workflows, expression systems, and CLD methodologies used to generate recombinant CHO cell lines for protein biologics manufacturing. Responsibilities include designing next-generation vector topologies using advanced cloning strategies (e.g., Gibson assembly, Golden Gate cloning) and supporting high-throughput, automated vector construction pipelines. This position directly supports development programs within a robust biologics pipeline and involves frequent cross-functional collaboration with global CMC partners across the U.S. and Europe.

    Key Responsibilities

    + Design and construct expression vectors using advanced molecular cloning techniques (Gibson assembly, Golden Gate cloning, restriction enzyme cloning, site-directed mutagenesis)

    + Develop, optimize, and implement automated, high-throughput vector construction and DNA assembly workflows on liquid handling platforms

    + Generate, validate, and bank vector constructs for expression of candidate biotherapeutics in mammalian cell systems

    + Perform molecular characterization using ddPCR, Sanger sequencing, restriction mapping, and related techniques

    + Support NGS library preparation for genomic and transcriptomic analysis of CHO cell lines

    + Troubleshoot and optimize molecular biology protocols to improve efficiency, robustness, and reproducibility

    + Prepare technical reports and presentations to communicate data, findings, and project progress

    + Maintain detailed electronic laboratory notebooks and accurate experimental documentation

    Basic Qualifications

    + PhD (0–3 years of postdoctoral or industry experience) in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related field

    + Strong hands-on experience with molecular cloning techniques including Gibson assembly, Golden Gate cloning, restriction cloning, and PCR-based methods

    + Demonstrated expertise in DNA construct design, vector engineering, and plasmid preparation

    + Experience with genetic characterization methods (ddPCR, qPCR, gel electrophoresis, DNA sequencing analysis)

    + Proficiency in designing and optimizing workflows for automation on liquid handling platforms (Hamilton, Tecan, or similar)

    + Excellent attention to detail with strong troubleshooting and problem-solving skills

    + Self-motivated, well-organized, and effective communicator with the ability to manage multiple priorities

    + Proven ability to work collaboratively in a team environment while meeting project timelines

    Preferred Qualifications

    + Mammalian cell culture experience in a pharmaceutical or biotechnology setting, particularly with CHO cells

    + Experience with high-throughput screening and clone selection strategies

    + Familiarity with sequence analysis and in silico cloning tools (SnapGene, Benchling, Geneious, Primer3, or similar)

    + Understanding of CHO cell line development and recombinant protein expression workflows

    + Experience with Oxford Nanopore Technologies or other NGS platforms

    + Basic programming or data analysis skills in R or Python

    + Experience with command-line or Bash scripting for bioinformatics workflows

    + Exposure to automated colony picking and clone tracking systems

    + Adaptability in a fast-paced, goal-driven research environment with a willingness to expand technical skillsets

     

    Benefit offerings include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, EAP program, commuter benefits and 401K plan. Our program provides employees the flexibility to choose the type of coverage that meets their individual needs. Available paid leave may include Paid Sick Leave, where required by law; any other paid leave required by Federal, State, or local law; and Holiday pay upon meeting eligibility criteria.

     

    **Pay Details:** $50.00 to $57.90 per hour

     

    Benefit offerings available for our associates include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, EAP program, commuter benefits and a 401K plan. Our benefit offerings provide employees the flexibility to choose the type of coverage that meets their individual needs. In addition, our associates may be eligible for paid leave including Paid Sick Leave or any other paid leave required by Federal, State, or local law, as well as Holiday pay where applicable.

     

    Equal Opportunity Employer/Veterans/Disabled

     

    Military connected talent encouraged to apply

     

    To read our Candidate Privacy Information Statement, which explains how we will use your information, please navigate to https://uat.adecco.com/en-us/candidate-privacy

    The Company will consider qualified applicants with arrest and conviction records in accordance with federal, state, and local laws and/or security clearance requirements, including, as applicable:

    + The California Fair Chance Act

    + Los Angeles City Fair Chance Ordinance

    + Los Angeles County Fair Chance Ordinance for Employers

    + San Francisco Fair Chance Ordinance

    **Massachusetts Candidates Only:** It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.