• Postdoctoral Fellow - Computational Biophysics

    Genentech (South San Francisco, CA)


    The Position

    A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.

    A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the Computational Biophysics Team in the Department of Pharmaceutical Development at Genentech. Our computational biophysics team drives the development of advanced, physics-based _in silico_ methods aimed at understanding the developability properties of therapeutic molecules and providing molecular-level insights. By supporting research and development teams, we enable the implementation of mitigation strategies and facilitate informed decision-making to achieve long-term molecular stability. This postdoctoral position offers an opportunity to contribute to development-focused initiatives. Key areas include generating a molecular-level understanding of self-association and developing guiding tools and methods to support formulation development. Candidates with experience in protein self-association, interfacial behavior, and the effects of salts are especially encouraged to apply.

    The Opportunity:

    + You will have opportunities to productively collaborate with other researchers across departments, present your work to project teams, and contribute to scientific publications.

    + The successful candidate will be integral to the Pharmaceutical Development Department, collaborating with experts to advance the understanding of key considerations in formulation development and to elucidate the molecular mechanisms governing stability in therapeutic formulations using in silico methods.

    + You will be part of the Genentech post-doctoral training program and the Pharmaceutical Development Innovation Team offering an exceptional environment and the opportunity to pursue fundamental science questions within a context focused on drug development and breakthrough discoveries.

    Who You Are:

    + Ph.D. with a proven track record of excellence in computational biophysics and/or computational chemistry.

    + Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal.

    + Independent scientist with outstanding communication skills, a strong passion and commitment to science, who works well within a team

    + Excited about supporting large molecule therapeutic development

    Preferred Qualifications:

    + Hands-on experience in molecular dynamics simulations, particularly with antibodies and/or proteins is required. Experience with co-solvent MD, is highly desired.

    + A proven track record of successfully developing _in silico_ methods to provide mechanistic explanations for experimental observations is required.

    + Working knowledge of basic machine learning is a plus.

     

    The expected salary range for this position based on the primary location of South San Francisco California is $110,000 and $120,000.. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.

     

    Benefits (https://roche.ehr.com/default.ashx?CLASSNAME=splash)

     

    Relocation benefits are available for this job posting.

     

    Postdoc Program

     

    Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

     

    The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.

     

    The Genentech Postdoc Program (http://careers.gene.com/us/en/students-postdocs) provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

     

    Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

     

    If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (https://docs.google.com/forms/d/e/1FAIpQLSdZWlsbfQOvFVIQgHE\_iDzWUTlhZvj6FytIzjS7xq6IGh1H5g/viewform) .