• Senior Scientist

    Actalent (Thousand Oaks, CA)


    Sr Scientist

     

    Department: Center for Technology Innovation (CfTI), Amgen

    Role Overview

    Amgen’s Center for Technology Innovation (CfTI) is seeking a highly motivated Computational Biologist to support our clinical portfolio through advanced analytics, biomarker development, and innovative computational approaches. This high‑visibility individual contributor role partners across matrixed teams to design, implement, and apply analytical methods that drive patient selection, biomarker strategy, and clinical decision‑making.

     

    The ideal candidate brings strong expertise in clinical bioinformatics, statistical modeling, and biological data analysis, with hands‑on experience working with clinical datasets. Experience in prostate cancer or solid tumor biology is highly desirable.

    Key Responsibilities

    + Develop and apply computational, statistical, and machine learning methods to analyze multi‑modal, multi‑dimensional, and large‑scale clinical and translational datasets.

    + Translate biological and clinical questions into rigorous analytical frameworks that generate actionable insights.

    + Support biomarker discovery and clinical assay development across flow cytometry, IHC, NGS, immunoassays, imaging, and transcriptional profiling platforms.

    + Collaborate across highly matrixed teams to drive scientific and technical innovation within CfTI and the broader Amgen research community.

    + Contribute to patient‑selection strategies, time‑series and survival analyses, and clinical data integration efforts.

    + Ensure analytical rigor and compliance with assay qualification requirements for clinical trial support.

    Basic Qualifications

    + PhD in Bioinformatics, Mathematics, Statistics, Computer Science, Data Science, or a related field;

    + OR M.S. with 3+ years of relevant industry experience.

    Preferred Qualifications

    + Significant experience in bioinformatics, applied mathematics, and/or statistics, including linear mixed‑effects modeling.

    + Working knowledge of machine learning and AI technologies; experience applying ML/AI in clinical trial settings is a plus.

    + Hands‑on experience with clinical biomarker platforms (flow cytometry, IHC, NGS, immunoassays, imaging, transcriptional profiling).

    + Deep understanding of prostate cancer or solid tumor biology.

    + Proficiency in R and Python, including tidyverse principles.

    + Familiarity with assay development and qualification for clinical trial support.

    + Strong communication skills, self‑motivation, and the ability to lead and influence in a matrixed environment.

     

    Job Type & Location

     

    This is a Contract position based out of Thousand Oaks, CA.

    Pay and Benefits

    The pay range for this position is $45.00 - $47.00/hr.

     

    Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following: • Medical, dental & vision • Critical Illness, Accident, and Hospital • 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available • Life Insurance (Voluntary Life & AD&D for the employee and dependents) • Short and long-term disability • Health Spending Account (HSA) • Transportation benefits • Employee Assistance Program • Time Off/Leave (PTO, Vacation or Sick Leave)

     

    Workplace Type

     

    This is a fully remote position.

     

    Application Deadline

     

    This position is anticipated to close on Jan 16, 2026.

    About Actalent

    Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

     

    The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

     

    If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email [email protected] (%[email protected]) for other accommodation options.