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Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC targeted protein degraders, that are designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets, the company has three investigational clinical-stage programs currently enrolling: ARV-102 for the treatment of patients with neurodegenerative disorders,ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas, and ARV-806, a KRAS G12D PROTAC for the treatment patients with solid tumors with KRAS G12D mutations.

On August 8 th 2025, the U.S. Food and Drug Administration (FDA) accepted the New Drug Application (NDA) for vepdegestrant- an investigational, orally bioavailable PROTAC estrogen receptor degrader- for its use as a monotherapy in the treatment of adults with estrogen receptor–positive (ER+), human epidermal growth factor receptor 2–negative (HER2-), ESR1-mutated advanced or metastatic breast cancer previously treated with endocrine-based therapy. In September 2025, Arvinas and Pfizer announced their plan to jointly select a third party for the out-licensing and commercialization of vepdegestrant.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

\#TeamArvinas is made up of passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and mission – to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC protein degradation platform. We’re really excited about the work we’re doing inside and outside of Arvinas, and think you will be, too. But don’t just take our word for it –  learn more about life at Arvinas and what employees have to say .

For more information, please visit www.arvinas.com .

Position Summary

The Associate Director, Clinical Development & Medical Affairs Operations plays an integral role in supporting the Medical Affairs organization. This position will be responsible for operational management of various projects and programs within Medical Affairs, and in partnership with cross-functional stakeholders.

This position reports to the Executive Director, Medical Affairs Operations, and may be located at our headquarters in New Haven, CT or may be performed remotely from a location within the U.S.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

+ Provides operational support to Medical Affairs department and projects, including managing project timelines and budget

+ Supports scientific publications operations, including publication tracking and reporting, author and agency coordination, document and journal submission management, compliance reviews, and maintenance of the Medical Affairs publications site

+ Assists in the planning and execution of congress activities

+ Assists in the planning and execution of Advisory Boards to include FMV assessments, tracking consultant agreements, and ensuring proper documentation

+ Coordinates Medical Review Committee process for review of scientific exchange materials

+ Manages the contracting process with external consultants/vendors and tracks progress

+ Coordinates functional team meetings and generates and distributes meeting minutes

+ Collaborates with internal cross functional stakeholders to ensure timely, quality execution of activities and projects

+ Supports cross-functional communication across the CDMA functional teams through appropriate methods

+ Supports high-priority, cross-functional initiatives that advance AI adoption, digital enablement, and other strategic CDMA priorities

+ Supports the development and execution of the AI, automation, and digital enablement strategy for CDMA, driving solutions that enhance productivity, operational efficiency, and decision making across functions

Qualifications

+ Minimum of 5 years of experience in pharmaceutical/biotechnology industry or related fields

+ Experience in medical affairs operations is preferred

+ Must be able to work independently and collaboratively in a fast-paced, matrixed, team environment consisting of internal and external team members.

+ Superior communication and interpersonal skills; effective interaction with cross functional team members.

+ Demonstrated planning, organization, and time management skills including the ability to support and prioritize multiple projects.

+ Demonstrated high level of competence with computers is essential; to include extensive experience with MS Office Applications is required

+ Must be legally authorized to work in the US without the need for employer sponsorship now or at any time in the future.

+ The duties of this role are generally conducted in a home office environment. Employees must be able, with or without an accommodation to use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Education

+ Bachelor’s degree in Life Sciences or Pharmacy.

_Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit_ _www.arvinas.com_

_Arvinas is an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identify, national origin, disability or protected veteran status._