- AbbVie (South San Francisco, CA)
- …AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. ... We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us… more
- Lilly (San Diego, CA)
- …to multiple work streams, including in vitro display systems for novel antibody discovery, flow cytometry applications, and recombinant antibody expression and ... immunogenicity profiles + Use biochemical and functional assays to evaluate antibody -antigen interaction including ELISA, cell binding and signaling assays, Octet or… more
- Gilead Sciences, Inc. (Foster City, CA)
- …Principal Scientist to contribute to the engineering of Multispecific formats, novel antibody binding domains, fusion proteins (eg cytokines), as well as to the ... through differentiated mechanisms of action + Drive rapid optimization of novel antibody and protein therapeutics through iterative design, build, test, and learn… more
- Gilead Sciences, Inc. (Foster City, CA)
- …aspects of downstream process development, including protein purification, bioconjugation ( antibody -drug conjugates), and new technology implementation. + Design and ... expertise in protein purification (chromatography, depth/membrane filtration, ultrafiltration/TFF) and antibody -drug conjugates. + MS degree with at least 6 years… more
- Lilly (San Diego, CA)
- …including mammalian (CHO and HEK293), bacterial, and insect cells to support antibody /peptide discovery projects + Evaluate and implement new methods for protein ... and external collaborations + Provide critical insights into antigen design for antibody discovery and structural studies, leveraging AI/ML approaches and large data… more
- Amgen (Thousand Oaks, CA)
- …explore new technologies that will contribute to the next generation of antibody drug conjugates. The Hybrid Modalities Group in the Complex Biologics Department ... biology to apply their synthetic skills in developing novel linkers for antibody drug conjugates. + Evaluate novel conjugation methods. + Design, synthesize, and… more
- The County of Los Angeles (Los Angeles, CA)
- …procedures. + Draws, groups, types, and cross-matches donor-recipient blood; performs antibody screening tests and antibody identification tests to resolve ... the specialty of immunohematology including ABO/Rh Type or Group, unexpected antibody detection, compatibility testing and antibody identification. Clinical… more
- Eurofins US Network (Fremont, CA)
- …signaling pathways, protein function, and immunoassay theory. Experience in antibody conjugation, immunoassay development, and buffer optimization. + Experience in ... of linkers, experience in TR-FRET based buffer optimization, and experience in antibody screening. + Proficiency in data analysis using GraphPad Prism or equivalent… more
- Gilead Sciences, Inc. (Foster City, CA)
- …Your contributions will directly shape the future of biologics and antibody therapeutics. **What** **You'll** **Do** + Develop advanced computational workflows for ... dynamics packages (AMBER, GROMACS, etc) is a plus. + Familiarity with antibody structure and protein engineering principles. + Proficiency in Linux environments and… more
- Lilly (South San Francisco, CA)
- …requires comprehensive knowledge in small molecule drug development, ADME/Tox, antibody engineering, and/or genetic medicine, combined with expertise in data ... benchmark federated models against public datasets (ChEMBL, PubChem, PDB, Therapeutic Antibody Database) to establish performance baselines and identify gaps. +… more