- Beth Israel Lahey Health (Boston, MA)
- …pathogens. 2. Performs in vitro tissue culture-based immune assays to study antibody mediated immunity to COVID-19, HIV-1, and other emerging pathogens in humans. ... 3. Maintains and updates procedures and regulatory documentation associated with GCLP clinical trial work and other various research programs. 4. Coordinates the shipment, transport, and tracking of study specimens from the laboratory's affiliated clinical… more
- Massachusetts Institute of Technology (Cambridge, MA)
- …for nucleic acids as well as peptides and proteins; oligonucleotide- antibody conjugation and purification; gel electrophoresis; purification plus quantitative ... analysis of nucleic acids and their products using centrifugation, PCR and qPCR, dialysis, HPLC, PAGE, agarose gel electrophoresis, and analytical mass spectrometry; lab management and supplies coordination, including assisting researchers with routine… more
- Takeda Pharmaceuticals (Boston, MA)
- …sequences, experimental data, or computational biology pipelines** (eg, protein or antibody engineering, `omics analysis, etc.). + Experience working with **large ... datasets** (NGS, high-throughput screens, bioassays) for supervised or unsupervised model training and evaluation. + Deep familiarity with **agentic AI design** : planning agents, tool-using agents, memory-augmented LLMs, or lab automation interfaces (eg, lab… more
- Takeda Pharmaceuticals (Boston, MA)
- …in large molecule discovery (including areas like protein engineering and antibody discovery). + Proven leadership and experience in scientific workflow design ... and process optimization, particularly within AI/digital and lab automation initiatives. + Track record in driving large-scale transformations and visionary changes. + Comprehensive understanding of the challenges and opportunities in large molecule discovery,… more
- Dana-Farber Cancer Institute (Boston, MA)
- …immunogen design and innovative vaccine strategies aimed at enhancing subdominant antibody responses. Mouse model immunization studies, immune sera analyses, FACS ... for immune cells analyses, B cell repertoire analysis and immunohistology are key tasks along with cloning, expression and purification of proteins, cell culture, etc. Highly-motivated candidates with a recent PhD or MD/PhD in biomedical sciences and… more
- Sanofi Group (Cambridge, MA)
- …areas at Sanofi and with a scope that includes small molecule, monoclonal antibody , peptide, gene therapy including nucleic acid modalities. The individual in this ... position is an integral part of the therapeutic area project teams and cross-functional Translational Medicine Subteam from preclinical development through post-marketing. A key focus of this role is the path from the research phase through early clinical… more
- ThermoFisher Scientific (Burlington, MA)
- …solutions for BioPharma and Biotech customers, with a focus on monoclonal antibody (mAbs) therapeutics. This is an exciting and evolving market that requires ... multifaceted and adaptable marketing efforts. **A day in the Life:** The candidate in this role will need to successfully work within a highly matrixed organization to develop global, multi-channel marketing campaigns, and build and manage tactical execution… more
- Sanofi Group (Framingham, MA)
- …next 5 years including monoclonal and multi-specific antibodies, fusion proteins, antibody -drug conjugates, synthorins and nanobodies. In recent years we have ... successfully established second-generation manufacturing process with a continuous process platform. We are pursuing future innovations such as digital labs, factories of future and advanced analytics-based process understanding and control. We are an… more
- Sanofi Group (Framingham, MA)
- …team, constructing a generic kinetic model to estimate stability of monoclonal antibody products in development. This will allow teams to create a benchmarking ... model for evaluating molecules with limited stability data. We are seeking a candidate to collect relevant data and populate the kinetic model within the AKTS software. This position will provide experience in statistical modeling and database creation in the… more
- Sanofi Group (Cambridge, MA)
- …Perform experiments to characterize targets and pathways to select functional antibody or small molecule therapeutic candidates. Hands-on laboratory contribution is ... essential. + Maintain cell cultures and perform reporter assays as well as other in vitro assays including, but not limited to ELISA, MSD, and Flow Cytometry. + Assist with in vivo pharmacology studies by performing injections and assisting with sample… more