- MD Anderson Cancer Center (Houston, TX)
- …uses unbiased, high-throughput technologies to decode the rules of interaction among diverse cell types in the tumor milieu that determine patient outcomes to cancer ... immunotherapy, primarily in hematologic malignancies (NEJM 2016; Cell 2018; Sci Transl Med 2020; Blood 2021; Cell Reports 2021; Cancer Cell 2023). We are… more
- MD Anderson Cancer Center (Houston, TX)
- …therapies. Designs and generates transgene vectors for expression of TCRs, CARs, T- cell engagers, tumor antigens, and other genes to be introduced into cells. ... guides for gene knock-out or knock-in. Leads production of biologics (T- cell engagers, peptides, minigenes, phage) in appropriate producer cells (mammalian,… more
- Texas A&M University System (College Station, TX)
- …and fast-paced, having multiple collaborating labs in mammalian cell biology, microbiology, biotechnology, and engineered microdevices. The candidate ... including postdoctoral researchers and graduate students. Responsibilities: + Perform mammalian cell culture and maintenance + Perform and support mammalian cell… more
- MD Anderson Cancer Center (Houston, TX)
- …responsibility will be to assist in the computational analysis of spatial single- cell transcriptomic and proteomic data from patient tumors generated from platforms ... involve identifying spatially localized cellular niches, characterizing immune and epithelial cell states, modeling cell - cell communication, and uncovering… more
- MD Anderson Cancer Center (Houston, TX)
- Tumor Microenvironment, Cancer Cell Biology and Genomics The Bullman Laboratory at the Department of Immunology, chaired by Dr. James P. Allison, is seeking a highly ... a Postdoctoral Fellow with a strong background in cancer cell biology, lineage tracing, and cell and molecular biology. The position will focus on uncovering… more
- MD Anderson Cancer Center (Houston, TX)
- …seeks to understand how the tumor microenvironment is spatially organized, what cell - cell interactions drive the emergence of spatial heterogeneity, and how ... the fibroblast wiring diagram across tissues and diseases. Using high-throughput single- cell approaches combined with CRISPR-based screens in vivo, we'll map how… more
- MD Anderson Cancer Center (Houston, TX)
- …and cells of the tumor microenvironment as well as tumor-immune-stroma crosstalk at single- cell resolution and in the spatial context. The lab's key focus areas ... therapies and the development of therapeutic resistance. Leveraging cutting-edge single- cell and spatial multi-omics technologies, cellular imaging, and innovative… more
- MD Anderson Cancer Center (Houston, TX)
- …associated with therapeutic response and resistance to RAS inhibition in non-small cell lung cancer (NSCLC) in the laboratory of Ferdinandos Skoulidis, MD, PhD, ... vitro assays (such as drug screening, flow cytometry, development of resistant cell lines) and in vivo experiments using xenograft, syngeneic and genetically… more
- MD Anderson Cancer Center (Houston, TX)
- …position will involve basic and translational research in the area of brain tumor cell biology and mouse models of primary and metastatic brain cancer. There will be ... mouse models and in vitro culture systems to study cell adhesion and signaling pathways involved in tumor ...cell adhesion and signaling pathways involved in tumor cell -stromal cell interactions. Biochemical, molecular genetical and… more
- MD Anderson Cancer Center (Houston, TX)
- …to join our team. Our laboratory focuses on understanding how dysregulation of cell - cell interactions shape tumor development and drive immune evasion - a ... and computational approaches in the areas of functional genomics, single cell /spatial multi-omics, cell biology, biochemistry, data mining, machine learning,… more