- UTMB Health (Galveston, TX)
- …is to better understand the in vivo processes that contribute to B cell competition following vaccination with complex vaccine-relevant antigens. In this light we ... a better understanding of these processes in HIV vaccine candidates utilizing B cell transfer models (Immunity 2018 and PNAS 2020 (PMIDs:29287996 & 32873644)). The… more
- MD Anderson Cancer Center (Houston, TX)
- …responsibility will be to assist in the computational analysis of spatial single- cell transcriptomic and proteomic data from patient tumors generated from platforms ... such as CosMx Spatial Molecular Imager. Analyses will involve identifying spatially localized cellular...identifying spatially localized cellular niches, characterizing immune and epithelial cell states, modeling cell - cell communication,… more
- MD Anderson Cancer Center (Houston, TX)
- …seeks to understand how the tumor microenvironment is spatially organized, what cell - cell interactions drive the emergence of spatial heterogeneity, and how ... the fibroblast wiring diagram across tissues and diseases. Using high-throughput single- cell approaches combined with CRISPR-based screens in vivo, we'll map how… more
- MD Anderson Cancer Center (Houston, TX)
- …research projects related to cancer development and drug resistance . Performs single- cell RNA-seq profiling using tumor biopsies from animal models of cancer and ... conducts computation analysis, generates hypothesis and performs experimental validation of single- cell RNA-seq findings in animal models of cancer and human samples… more
- The University Of Texas At Dallas (Dallas, TX)
- …seeking a highly motivated Post-Doctoral Research Associate interested in understanding the molecular and cellular mechanisms alterations in host cell metabolism ... infection, with an emphasis in spatial metabolic signatures. Classical biochemical and molecular biology approaches as well as state of the art metabolomics and… more
- MD Anderson Cancer Center (Houston, TX)
- …postdoctoral fellows to join a multidisciplinary research program in the molecular epidemiology of lymphoid malignancies. Based in the Departments of Epidemiology ... The University of Texas MD Anderson Cancer Center, our work bridges molecular , population, and clinical research. We investigate how inherited genetic variation,… more
- MD Anderson Cancer Center (Houston, TX)
- …the immune-mediated mechanisms of tumor response and resistance to therapy in non-small cell lung cancer. This fellowship offers a unique and exciting opportunity to ... as standard-of-care chemoimmunotherapy regimens in patients with surgically resected non-small cell lung cancer. If you are passionate about translating scientific… more
- UTMB Health (Galveston, TX)
- …for curious and motivated individual with strong research background in molecular biology, immunology, and other relevant, standard techniques. The candidate will ... apply advanced molecular , imaging, and omics techniques to study protein-protein, protein-DNA...techniques to study protein-protein, protein-DNA and protein-RNA interactions in cell culture and animal models. Strong oral and written… more
- Texas Tech University Health Sciences Center - El Paso (El Paso, TX)
- …RNA/protein isolation, qRT-PCR, cloning, mutagenesis, and transient/stable gene manipulation incancer cell lines. Culture 2D and 3D cancer spheroid models, including ... microscopy to assess subcellular localizationand phenotypic markers. + Perform live- cell imaging and apoptotic/mitotic readouts (Annexin V, TUNEL, Ki-67, H2AX,… more
- UTMB Health (Galveston, TX)
- …toxicity in protein aggregates. + Apply biochemical, biophysical, immunological, molecular methods to characterize amyloidogenic proteins and aggregates polymorphs + ... in tau aggregation and the mechanism of their toxicity and spreading in cell models, primary cultures, and animal models + Perform experiments, analyze data and… more