- Amgen (Thousand Oaks, CA)
- …Assays for Key Residual Host Cell Proteins + **Drug Product Technology -** Using Mass Spectrometry as an In-line Process Analytical Tool for Lyophilization + ... **Combination Product Operations** - Gathering Patient and Internal Stakeholder Insights to Improve Combination Products and Processes + **Manufacturing and Clinical Supply** - Tactical Project Management Standardization for Commercial Drug Product Tech… more
- Amgen (Thousand Oaks, CA)
- …Assays for Key Residual Host Cell Proteins + **Drug Product Technology -** Using Mass Spectrometry as an In-line Process Analytical Tool for Lyophilization + ... **Combination Product Operations** - Gathering Patient and Internal Stakeholder Insights to Improve Combination Products and Processes + **Manufacturing and Clinical Supply** - Tactical Project Management Standardization for Commercial Drug Product Tech… more
- Amgen (Thousand Oaks, CA)
- …Responsibilities: + Generate, analyze, and critically evaluate analytical data (LC, CE, mass spectrometry , and related methods). + Support analytical method ... optimization, method verification, troubleshooting. + Provide technical leadership and identify opportunities for automation to reduce manual, repetitive tasks. + Actively contribute to process improvements and strategy development that promote consistent and… more
- Cedars-Sinai (Los Angeles, CA)
- …Knowledge of safety standards and maintenance of specialized equipment. + Knowledge of mass spectrometry , tracer studies and transgenic mouse models. + Expertise ... in biological data science and data-driven discovery, scientific programming and omics data analysis, genetics will also be beneficial, as is communicating results in scientific conferences and papers. **About Us** Cedars-Sinai is a leader in providing… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …+ Basic bench research experience: Biochemistry, nucleic acid, proteomics (2-D and Mass spectrometry ), molecular genetics, hiPSCs culture and phenotyping assays, ... histopathology and confocal imaging, protein-protein interaction assays, CHIP, CLIP, and CHIRP assays. + Animal (mouse) breading, handling, injection methods, phenotypic characterization, cardiovascular physiology and echocardiography imaging, genetic… more
- Gilead Sciences, Inc. (Foster City, CA)
- …+ Experience with ADC characterization methods including SEC, HIC, RPLC, and high-resolution mass spectrometry methods for DAR assessment. + Experience with the ... use of preparative methods for ADC purification. + Familiarity with automation platforms for high-throughput conjugation. + Familiarity with enzymatic conjugation methods. + Familiarity with traditional and next generation bioconjugation handles + Experience… more
- Gilead Sciences, Inc. (Foster City, CA)
- …or more of the following techniques: solution state nuclear magnetic resonance, mass spectrometry , and/or solid state characterization (FTIR, XRPD, DSC/TGA, ... etc.) + Flexibility to support changes in project priorities and be able to adapt to fast paced working environment **People Leader Accountabilities:** + Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the… more
- Amgen (Thousand Oaks, CA)
- …biochemists, structural biologists, medicinal chemists, computational biologists, pathologists, and mass spectrometry experts to inform experimental design and ... data interpretation. **Innovation and Scientific Rigor** : Contribute to the development and application of cutting-edge technologies. Proactively propose and explore novel hypotheses to uncover new therapeutic opportunities in obesity and cardiometabolic… more
- Amgen (South San Francisco, CA)
- …profiling efforts for functional genomics studies. + Prepare high-quality samples for mass spectrometry (eg, TMT, DIA) and next-generation sequencing. + Use ... cutting-edge software tools (eg, Cell Ranger, Seurat, Proteome Discoverer, Spectronaut, DIA-NN) and collaborate with bioinformatics to analyze and interpret high-dimensional datasets. + Collaborate across multidisciplinary teams to drive integrated multi-omics… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …activity; 3) in vitro studies such as site-directed mutagenesis and immunoprecipitation- mass spectrometry to identify binding partners for proteins and ... how these affect cellular responses to stress; and, 4) developing new ex vivo models from human lung specimens for investigating the pathogenesis of lung injury and repair. with the goal of applying these techniques towards drug discovery. The candidate must… more