- Massachusetts Institute of Technology (Cambridge, MA)
- …and adventitious agent (AA) detection in sEV manufacturing based upon [1] rapid Mass Spectrometry detection of a metabolomic signature specific for bacterial ... contamination and [2] next-generation sequencing-based detection of sample contamination with AA genetic material. The performance of these methods will then be validated through spiking studies during continuous sEV manufacturing and ultimately integrate them… more
- Lilly (Boston, MA)
- …Biology, or related scientific field with 1+ years of experience with mass spectrometry . **Additional Skills/Preferences:** + HPLC based separation techniques is ... desired + Prior working knowledge and experience with AAVs and gene therapy. + Prior experience with oligonucleotide characterization is a plus. + Preferred having a good foundation in general scientific practice and the principles and concepts of a relevant… more
- Takeda Pharmaceuticals (Lexington, MA)
- …reaction (PCR), liquid chromatography (LC), gas chromatography (GC), electrophoresis, mass spectrometry (MS), nuclear magnetic resonance (NMR), immunoassays, ... lyophilization, dynamic light scattering (DLS), UV-Vis spectroscopy, etc.; Troubleshoot throughout the process to improve analytical methods and enhance yield; Analyze the data, draw conclusions from the results, and propose scientific and industrial… more
- System One (Andover, MA)
- …and protein quantitation assay experience. Responsibilities + Preparation of samples for mass spectrometry analysis + Design of experiments in collaboration with ... colleagues + Conduct analytical experiments and method development as needed + Identify and exploit new scientific concepts + Interpretation and documentation of experimental results + Communication of experimental results to team members + Maintain high… more
- AbbVie (Worcester, MA)
- …techniques such as HPLC, capillary electrophoresis, and other relevant methods. Experience with mass spectrometry and ELISA is a Plus. + Familiarity with USP/ICH ... guidelines for method development, qualification, and validation. Extensive experience in authoring, reviewing regulatory submissions and responding to agency information requests. + Strong technical and people leadership skills, and demonstrated ability to… more
- Sanofi Group (Framingham, MA)
- …isotopic labeling experiments, perform intracellular metabolite extraction, and analyze untargeted mass spectrometry data. + The candidate should be comfortable ... interpreting experimental results such as growth rates, nutrient uptake/secretion, intracellular metabolite levels, and isotopologue distributions. + The candidate will also be able to prepare cell culture samples for LC-MS analysis using automated liquid… more
- Boston College (Chestnut Hill, MA)
- …imaging. Other core facilities include a nanofabrication, bioinformatics server, mass spectrometry , flowcytometry, NMR and X-ray crystallography facility. ... The following are examples of typical duties, but other duties may also be assigned. + Development of the research project including planning and designing experiments, data analysis. + Presentation of project results at meetings and seminars. + Publication of… more
- Serco (MA)
- …+ May require a familiarity with various other organic, inorganic andhigh-resolution mass spectrometry (HRMS) methods + Prepare detailed, professional reports on ... findings + Manage electronic data across platforms + Monitor workflow, backlogs, and performance metrics + Conduct SOP reviews as needed + Trend and monitor key performance metrics. + Technical support in development,review, and/or revision of QA-related… more
- Charles River Laboratories (Shrewsbury, MA)
- …drug molecules from biological matrices, oversee analysis of samples by mass spectrometry , review/interpret bioanalytical results, and prepare/QC data summaries ... under the guidance of more senior staff members. The successful candidate will have excellent attention to detail, strong communication and interpersonal skills, and the ability to work collaboratively in a fast-paced team environment. **Job Qualifications**… more
- ICF (Boston, MA)
- …Like You to Have** + Advanced degree in chemisty + Experience in high-resolution mass spectrometry (HRMS) for dioxins and furans + Radiochemistry analysis of ... environmental matrices (soil, water, air) and data validation of radiochemistry data following MARLAP guidance + Recent experience with data validation using the NFG + Experience with SMO Portal, EXES + Hands-on experience with LC/MS/MS for PFAS/PFO **\#ESAT**… more