- AbbVie (South San Francisco, CA)
- …Leverage prior experience leading analytical efforts focused on phase appropriate peptide drug substance and drug product development. + Experience developing global ... Analytical Chemistry preferred) Experience with analytical aspects of advancing peptide modalities. + Proven scientific leadership; strong interpersonal and… more
- Kelly Services (Thousand Oaks, CA)
- …characterization efforts for a growing pipeline of bioconjugate and antibody/ peptide /oligo-based therapeutics. This role is critical to understanding conjugation ... and drug-to-antibody ratio (DAR) assessments. + Perform and interpret bottom-up peptide mapping in collaboration with chemists and protein engineers. + Analyze… more
- Lilly (Pasadena, CA)
- …Overview** The Post Doctoral Protein Biochemistry Research Scientist will focus on peptide synthesis and oral macrocycle efforts at Protomer. This includes the ... burden in terms of cost and/or time. + Provide support and lead peptide synthesis efforts including novel insulin generation and testing. + Ensure the analytical… more
- Lilly (Pasadena, CA)
- …chemical biology, specifically peptides and macrocycles with a particular focus on peptide libraries, and oral macrocyclic peptides. The Protomer team engages in ... **Responsibilities:** + Contribute to projects in oral macrocycles, chemical biology or peptide frameworks combining aspect of molecule design and conjugation at the… more
- Lilly (San Diego, CA)
- …following: + Bioassay development + Biological testing of compounds + Organic and Peptide synthesis + Chemical Modality + Molecular biology + Protein expression + ... in + Bioassay development, + Biological testing of compounds, + Organic and Peptide synthesis, + Chemical Modality, + Molecular biology, + Protein expression, +… more
- Astrix Technology (Los Angeles, CA)
- …other designated areas at the manufacturing facility + Develop peptide -manufacturing processes including peptide /protein purification by chromatography, ... crystallization, and other techniques, and in process test methods + Assist QA/QC for monitoring raw material inventories + Write Standard Operation Procedures, Standard Test Procedures, Master Batch Records and other related GMP documents + Follow SOPs and… more
- Catalent Pharma Solutions (San Diego, CA)
- …a team focused on the development of analytical methods for small molecule, peptide drug products and amorphous intermediates. This individual may be required to ... Catalent employee.** **The Role:** + Develop stability-indicating methods for peptide and small molecule API (Active Pharmaceutical Ingredient), amorphous… more
- University of Southern California (Los Angeles, CA)
- …researcher to investigate the mechanisms of modular polyketide and nonribosomal peptide biosynthesis. The selected individual will use biochemical and biophysical ... techniques, including single-particle cryogenic electron microscopy (cryo-EM), to understand the relationships between megasynthase structure and catalysis. The work entails additional opportunities to explore (1) the enzymology of as-yet undiscovered natural… more
- Amgen (Thousand Oaks, CA)
- …total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, conjugation chemistry and/or ... chemoinformatics/machine learning + Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry + Track record of peer-reviewed publications and research presentations + Demonstrated ability to work within a dynamic and… more
- Lilly (Pasadena, CA)
- …methods + Introduce and maintain innovative technologies with respect to peptide therapeutics, including developing and implementing assays and maintaining critical ... instruments. + Perform data analysis. Critically evaluate data and results and troubleshoot experiments. + Demonstrable ability to function independently, work within a team-oriented lab environment, and work within cross-functional project teams. + Maintain… more