- Cambrex High Point (Waltham, MA)
- …and capabilities, including continuous flow, controlled substances, liquid-phase peptide synthesis, solid-state science, material characterization, and highly potent ... seeking exceptional candidates for its Principal Scientist / Principal Engineer - Peptide Manufacturing position at its Waltham, MA R&D center. A successful… more
- AbbVie (Cambridge, MA)
- …Leverage prior experience leading analytical efforts focused on phase appropriate peptide drug substance and drug product development. + Experience developing global ... Analytical Chemistry preferred) Experience with analytical aspects of advancing peptide modalities. + Proven scientific leadership; strong interpersonal and… more
- Lilly (Boston, MA)
- …following: + Bioassay development + Biological testing of compounds + Organic and Peptide synthesis + Chemical Modality + Molecular biology + Protein expression + ... in + Bioassay development, + Biological testing of compounds, + Organic and Peptide synthesis, + Chemical Modality, + Molecular biology, + Protein expression, +… more
- Cambrex High Point (Waltham, MA)
- …and capabilities, including continuous flow, controlled substances, liquid-phase peptide synthesis, solid-state science, material characterization, and highly potent ... stability programs, outsourced testing management, and cross-site collaboration preferred. + Peptide and/or oligonucleotide analytical experience is a plus but not… more
- AbbVie (Worcester, MA)
- …+ Implement expansion of immunogenicity platform through MHC-II associated peptide proteomics (MAPPs) and real-time DC internalization assay development for ... large molecules using human DC/PBMC models. + Represent IVIS team on project meetings, designing & coordinating IVIS studies of biologic drug candidates. + Author publication, presentations, and/or regulatory documents. Qualifications Qualifications +… more
- Actalent (Andover, MA)
- …including N-glycan profiling, titer determination, Size Exclusion Chromatography (SEC), peptide mapping, imaged Capillary Isoelectric Focusing (iCE), and Capillary ... Gel Electrophoresis (CGE). + Utilize Mass Spectrometry (MS) for structural and functional characterization of biologics. + Interpret complex data sets and provide clear, actionable insights to cross-functional teams. + Ensure compliance with GMP standards and… more
- Cambrex High Point (Waltham, MA)
- …and capabilities, including continuous flow, controlled substances, liquid-phase peptide synthesis, solid-state science, material characterization, and highly potent ... APIs. Your Work Matters. At Cambrex, we strive to build a culture where all colleagues have the opportunity to: + engage in work that matters to our customers and the patients they serve + learn new skills and enjoy new experiences in an engaging and safe… more
- System One (Andover, MA)
- …specifically N-glycan analysis, titer determination, Size Exclusion Chromatography (SEC), peptide mapping, imaged Capillary Isoelectric Focusing (iCE), and Capillary ... Gel Electrophoresis (CGE) along with some Mass Spectroscopy (MS) experience to characterize mAbs and other proteins. + Experience with BioAccord systems highly desired Benefits System One offers eligible employees health and welfare benefits coverage options,… more
- Takeda Pharmaceuticals (Boston, MA)
- …(eg, AlphaFold-Multimer/ESMFold/OpenFold) and pocket-guided design. + Physics/ML hybrid methods; peptide modeling with **non-canonical amino acids** . + Data systems ... (SQL/NoSQL), MLflow/Kubeflow/SageMaker; deployment on HPC/cloud. + Publications, preprints, or conference presentations; awards or open-source contributions. **Takeda Compensation and Benefits Summary** We understand compensation is an important factor as you… more
- Takeda Pharmaceuticals (Lexington, MA)
- …and biophysical techniques including liquid chromatography (LC), electrophoresis, peptide mapping, glycan mapping, quantitation of polysorbates, silver staining, ... freeze-drying microscopy (FDM), differential scanning calorimetry (DSC), differential scanning fluorimetry (DSF), subvisible particle analysis via micro-flow imaging (MFI) and HIAC system, FTIR, osmolality measurement, etc.; Develop and qualify analytical test… more