- Takeda Pharmaceuticals (Boston, MA)
- …methods for assessing on- and off-target activity, physical properties, pharmacokinetics / pharmacodynamics (PK/PD), and synthetic feasibility + Implement and ... execute innovative computational methodologies and tools such as AI-based drug discovery, state-of-the-art commercial and open-source software tools/methods + Mentor junior computational chemists on molecular design best practices + Open to traveling and… more
- Takeda Pharmaceuticals (Boston, MA)
- …by aligning with key stakeholders, including internal biology, pharmacokinetics , toxicology, computational sciences, and structural biology/protein chemistry teams. ... Collaborate extensively within interdisciplinary research teams in a matrix format (functional/report-line teams and research project teams) to advance discovery programs. + Serve as an inspirational global subject matter expert in Small Molecule In Vitro… more
- Merck (Boston, MA)
- …Building fruitful collaborations with stakeholders across medicinal chemistry, pharmacokinetics & pharmacodynamics, quantitative biosciences, and therapeutic area ... biology + Contributing to the continued scientific growth and development of both M&I and Chemistry colleagues as a mentor and influencer both locally and across our network + Contributing to the reputation of our Company's peptide capabilities through… more
- Takeda Pharmaceuticals (Boston, MA)
- …immunoglobulin therapies is of an advantage. + Experience with assessments of pharmacokinetics , toxicology and biodistribution studies as well as ADA and biomarker ... studies in various matrices and tissues (brain, spinal cord, liver, kidney, spleen, lymph nodes) to support both nonclinical and clinical studies is of an advantage. + Experience in discussing and presenting molecular basis of clinical manifestations,… more