- Frontier Medicines (South San Francisco, CA)
- …+ Extensive experience in structure-based-design, fragment -based drug discovery, ADME PK optimization and achieving challenging target product profiles. + Delivery ... of impactful patents and publications in medicinal chemistry. + Project leadership experience. + Experience in overseeing and directing day-to-day scientific activities of junior staff and CRO scientists. + A commitment to excellence, including ensuring that… more
- Pfizer (South San Francisco, CA)
- …of emerging program targets, priorities and status. + Implementation of PK -guided dose escalation, early combination strategies and emerging innovations on all ... and foster new research projects and programs. **BASIC QUALIFICATIONS** + MD or MD- PhD with 5-10 years of industry experience in oncology, experience in multiple… more
- Kelly Services (Thousand Oaks, CA)
- …LC-MS/MS, especially for intact protein analysis, peptide mapping, and bioanalytical PK quantification. + Familiarity with conjugation chemistry and its analytical ... implications. + Proven ability to oversee external CROs and manage mass spectrometry workflows under time-sensitive timelines. + **Preferred Skills:** + Experience with oligonucleotide/peptide mass spectrometry or detection in plasma/tissue matrices. +… more
- Merck (South San Francisco, CA)
- …molecules as potential drugs, including experience using computation to solve ADME/ PK issues + Experience performing quantum chemistry calculations with tools such ... as Gaussian or ORCA + Experience with one or more of the following: MOE, Schrodinger, OpenEye + Programming experience with a language such as Python or C for scientific computing + Strong written and oral communication skills, with demonstrated ability to… more
- Lilly (Pasadena, CA)
- …and professionally with colleagues at Protomer and across Lilly. **Qualifications:** PhD or post-doctoral degree in chemistry, synthetic chemistry, chemical biology ... within Medicine Innovation Hub, therapeutic areas, ADME, nonclinical safety assessment and PK /PD. + Open, transparent and able to communicate equally well with… more
- System One (Alameda, CA)
- …are consistent with regulatory guidance + Analyze and interpret preclinical pharmacokinetic and pharmacodynamic data to inform drug development decisions + Closely ... policies and general laboratory practices. EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS: + PhD degree in Pharmacokinetics, Drug Metabolism, Pharmaceutical Sciences, or… more
- Lilly (San Diego, CA)
- …Minimum 3-5 years of pharmaceutical industry experience in clinical development + PhD in Immunology, Molecular Biology, or related field strongly preferred + ... endpoints, biomarker strategies, precision medicine approaches, clinical pharmacology, and pharmacokinetic /pharmacodynamic modelingPrevious experience in autoimmune therapeutic areas (autoimmune, inflammatory,… more
- Astellas Pharma (South San Francisco, CA)
- …patent applications, and regulatory submission documents. **Required Qualifications** + PhD . in Chemistry, Biochemistry, Bioengineering, or a closely related field. ... technologies + Knowledge and experience in stability assessment of ADCs, pharmacokinetic (DMPK) characterization, and in vitro/in vivo efficacy evaluation. +… more
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