- Charles River Laboratories (Shrewsbury, MA)
- …as a Principal Investigator for the development and validation of biomarker, PK and ADA assays (eg: ligand binding assays, enzymatic assays, Luminex, Bioplex, ... equivalent in a scientific related discipline. Related Master's degree (MS/MA) or PhD /DVM preferred. Experience: Minimum of 6 years related experience in the… more
- Merck (Boston, MA)
- …mechanism of action studies to establish biochemical/biophysical and translational PK /PD relationships + Support pipeline programs across all therapeutic areas ... or targeted protein degradation considered a plus. **Education:** + PhD in biology, chemistry, biochemistry, chemical biology, pharmacology, biomedical sciences,… more
- Pfizer (Cambridge, MA)
- …of emerging program targets, priorities and status. + Implementation of PK -guided dose escalation, early combination strategies and emerging innovations on all ... and foster new research projects and programs. **BASIC QUALIFICATIONS** + MD or MD- PhD with 5-10 years of industry experience in oncology, experience in multiple… more
- Takeda Pharmaceuticals (Boston, MA)
- …model development and deployment, miniaturized high-throughput ADME screens, and real-time PK simulation. Required Qualifications + Minimum 10 years' experience in ... the pharmaceutical drug discovery process, with a focus on ADME studies. + Proven leadership and experience in scientific workflow design and process optimization, particularly within automation, digital integration, and AI/ML solution implementation in ADME… more
- Takeda Pharmaceuticals (Boston, MA)
- …on- and off-target activity, physical properties, pharmacokinetics / pharmacodynamics ( PK /PD), and synthetic feasibility + Implement and execute innovative ... as well as leading and mentoring computational chemistry teams. * PhD in Computational Chemistry, Chemical Physics, Medicinal Chemistry, or related disciplines,… more
- AbbVie (Cambridge, MA)
- …preclinical pharmacology studies to characterize compound activity and establish pharmacokinetic and pharmacodynamic relationships to drive compound optimization and ... inform human dose projections. + Contributes to preclinical study reports and documents to support Regulatory (IND/ CTA) filings, Investigator Brochures, and clinical study protocols and lab manuals. + Works effectively with cross-functional program and… more
- Sanofi Group (Cambridge, MA)
- …studies providing robust data for early Go/No Go decisions and other pharmacokinetic studies. + Supervise the execution and ensure close medical monitoring. + ... Review, interpret results, and author ECET-related clinical documentation, including informed consent forms, clinical protocols, study reports; some abstracts and/or manuscripts; clinical pharmacology or ECET components of investigator brochures, regulatory… more