- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** The Guccione Lab at the Icahn School of Medicine at Mount Sinai recently identified that inhibiting spliceosomal assembly through ... inhibition of arginine methylation provides an effective means of therapeutic splicing inhibition. Specifically, inhibiting either symmetric arginine methylation (mediated by the protein arginine methyltransferase 5 -PRMT5) or asymmetric dimethyl arginine… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** The post-doc will study mechanisms of blood-forming stem and progenitor cell fate determination and alteration in disease. One of the ... main tasks of the post-doc will be to interrogate the contribution of lysosomes and their communication with mitochondria to the regulation of blood forming stem cells and their alteration in leukemia. The post-doc will also carry experiments to identify… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** This is a Post-Doctoral Position in the Nephrology Division at the Icahn School of Medicine at Mount Sinai. The applicant will have a ... PhD, MD, or equivalent degree. The position requires familiarity with the principles behind basic renal physiology, glomerular disease, biomarker analysis and translational applications of these to clinical nephrology. The individual must be willing to… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Dr. Sahoo's laboratory studies epitranscriptomic- andexosomes-mediated mechanisms in pathologies and therapeutics of the heart. The ... projects involve a broad array of advanced techniques in exosomes and epitranscriptome biology, including MeRIP sequencing, confocal, super-resolution and electron microscopy, small non-coding RNAs, stable-isotope-labeling mass spectrometry, in vitro and in… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Alison Goate's laboratory in the Department Genetics and Genomic Sciences at the Icahn School of Medicine atMount Sinai (MSSM) in New ... York City is currently looking for highly skilled and motivated molecular/cellneuroscientists and neuroimmunologists to be the drivers of our efforts to translate the human genetics of Alzheimer'sdisease (AD) into effective preventative and therapeutic… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Dr. Alison Goate's laboratory in the Departments of Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at ... Mount Sinai (MSSM) in New York City is currently looking for highly skilled and motivated molecular/cell and functional genomics neuroscientists to be the drivers of our efforts to understand how the human genetics of the 17q21.31 "MAPT/tau" locus contributes… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Dr. Amaia Lujambio's research group studies mechanisms of liver cancer initiation and liver cancer maintenance. In particular, we are ... interested in how genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create vulnerabilities that may be targeted therapeutically. Our research interests involve the establishment of precision in vitro and in vivo… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** + Our group has recently identified that inhibiting spliceosomal assembly through inhibition of arginine methylation provides an ... effective means of therapeutic splicing inhibition. Specifically, inhibiting either symmetric arginine methylation (mediated by the protein arginine methyltransferase 5 -PRMT5) or asymmetric dimethyl arginine methylation (mediated by type I PRMTs (PRMT1, 3, 4,… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** At the Icahn Institute, our vision is to transform biomedical research and healthcare delivery into a data-driven, evidence-based, ... patient-tailored discipline. The Icahn Institute was founded in 2011 to help advance precision medicine with cutting-edge technologies, novel partnerships between the public and private sectors, and world class computational and analytical resources. By… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** The candidate will perform biochemical and genetic characterization of cyclin-dependent protein kinases (CDKs) involved in regulating ... gene expression in human cells. Specifically, candidatewill focus on the roles and regulation of Cdk7, an essential regulator of both cell-cycle progression and transcription. Candidate will use extant human cell lines previously generated by my lab that allow… more