- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** The candidate will perform biochemical and genetic characterization of cyclin-dependent protein kinases (CDKs) involved in regulating ... gene expression in human cells. Specifically, candidatewill focus on the roles and regulation of Cdk7, an essential regulator of both cell-cycle progression and transcription. Candidate will use extant human cell lines previously generated by my lab that allow… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Dr. Sahoo's laboratory studies epitranscriptomic- andexosomes-mediated mechanisms in pathologies and therapeutics of the heart. The ... projects involve a broad array of advanced techniques in exosomes and epitranscriptome biology, including MeRIP sequencing, confocal, super-resolution and electron microscopy, small non-coding RNAs, stable-isotope-labeling mass spectrometry, in vitro and in… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Alison Goate's laboratory in the Department Genetics and Genomic Sciences at the Icahn School of Medicine atMount Sinai (MSSM) in New ... York City is currently looking for highly skilled and motivated molecular/cellneuroscientists and neuroimmunologists to be the drivers of our efforts to translate the human genetics of Alzheimer'sdisease (AD) into effective preventative and therapeutic… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Renal Physiology Post-Doctoral Position This is a Post-Doctoral Position in a Renal Physiology Research Lab at the Icahn School of ... Medicine at Mount Sinai. The applicant will have a PhD, MD, or equivalent degree. The position requires familiarity with the principles behind basic renal physiology and molecular biology techniques, including genetic and physiologic analyses of mice. The… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Dr. Amaia Lujambio's research group studies mechanisms of liver cancer initiation and liver cancer maintenance. In particular, we are ... interested in how genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create vulnerabilities that may be targeted therapeutically. Our research interests involve the establishment of precision in vitro and in vivo… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** At the Icahn Institute, our vision is to transform biomedical research and healthcare delivery into a data-driven, evidence-based, ... patient-tailored discipline. The Icahn Institute was founded in 2011 to help advance precision medicine with cutting-edge technologies, novel partnerships between the public and private sectors, and world class computational and analytical resources. By… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** A post-doctoral position is immediately available in the Quantitative Body MRI research group at the BioMedical Engineering and ... Imaging Institute (BMEII) and the Department of Radiology at the Icahn School of Medicine at Mount Sinai in New York City The candidate will participate in various projects involving multiparametric MRI and radiomics in diffuse liver disease, MRI and PET-MRI… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** The Guccione Lab at the Icahn School of Medicine at Mount Sinai recently identified that inhibiting spliceosomal assembly through ... inhibition of arginine methylation provides an effective means of therapeutic splicing inhibition. Specifically, inhibiting either symmetric arginine methylation (mediated by the protein arginine methyltransferase 5 -PRMT5) or asymmetric dimethyl arginine… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** + Our group has recently identified that inhibiting spliceosomal assembly through inhibition of arginine methylation provides an ... effective means of therapeutic splicing inhibition. Specifically, inhibiting either symmetric arginine methylation (mediated by the protein arginine methyltransferase 5 -PRMT5) or asymmetric dimethyl arginine methylation (mediated by type I PRMTs (PRMT1, 3, 4,… more
- Mount Sinai Health System (New York, NY)
- …**_Roles & Responsibilities:_** Research which focuses on immune dysregulation in human diseases. 1) Multisystem Inflammatory Syndrome in Children (MIS-C) is a post ... SARS-CoV-2 viral inflammatory syndrome of unknown genetic etiology. Similarly, individuals with 2) Down syndrome (DS) present with increased susceptibility to an array of infectious diseases to autoimmunity. Unfortunately, the exact molecular mechanism… more