- Wacker Chemical (San Diego, CA)
- …perform upstream and downstream manufacturing processes on plasmid DNA (pDNA), mRNA, and protein . The PD Scientist I will support other scientists within the Process ... on upstream, downstream, and analytical processing of plasmid, mRNA, and protein manufacturing processes. Support other team members as needed in buffer/… more
- Merck (South San Francisco, CA)
- …scientific knowledge of the workflows required for the discovery and progression of protein therapeutics to development + State of the art knowledge and experience ... collaboration abilities **Preferred Experience and Skills:** + Experience in protein therapeutics beyond traditional mAbs including alternative non-Ig scaffolds, bi-… more
- Lilly (San Diego, CA)
- …and Peptide synthesis + Chemical Modality + Molecular biology + Protein expression + Purification, characterization, analytical methods, and formulation + Flow ... and Peptide synthesis, + Chemical Modality, + Molecular biology, + Protein expression, + Purification, characterization, analytical methods, and formulation, + Flow… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …genetics, hiPSCs culture and phenotyping assays, histopathology and confocal imaging, protein - protein interaction assays, CHIP, CLIP, and CHIRP assays. + ... Animal (mouse) breading, handling, injection methods, phenotypic characterization, cardiovascular physiology and echocardiography imaging, genetic manipulation of transgenic mice and overexpression systems. + Knowledgeable in Noncoding RNA, epigenetics, and… more
- Lilly (San Diego, CA)
- …of therapeutic areas. Integrating biology with innovative scientific capabilities in protein discovery, engineering and computational sciences, we are committed to ... data integration, and production workflows. + Partner with wet-lab discovery, protein engineering, information technologist and therapeutic area teams to translate… more
- Lilly (San Francisco, CA)
- …**Additional Preferences:** + Hands-on experience with biophysical assays for protein characterization, binding analysis and Molecular Dynamics (MD). + Experience ... in X-ray crystallography and cryo-EM data collection, processing, protein model and ligand building. + Experience in developing methods to identify ligand-ready… more
- Lilly (San Diego, CA)
- …idea generation, and prioritization. Use advanced computational techniques to study protein motions and interactions to understand the binding of small molecules ... free energy methods and enhanced sampling simulations techniques to provide novel protein conformational insights to help guide drug design efforts; 3 years of… more
- Lilly (San Diego, CA)
- …Eli Lilly and Company seeks a Senior Biologist (R2-R3) to conduct protein crystallization for X-ray crystallography structural analysis and sample preparation for ... field and 3 years of academic or employment experience with protein handling including dialysis, concentration, centrifugation. Academic or employment experience… more
- Gilead Sciences, Inc. (Foster City, CA)
- …various Research functions, including medicinal chemistry, structural biology, and protein therapeutics, to help advance transformational therapies into clinical ... to, mammalian cell culture, flow cytometry, cell-based assays, common protein quantification methods, and gene expression analysis. Experience with automation… more
- Cedars-Sinai (Los Angeles, CA)
- …cell culture (mouse and human), advanced molecular/cell biology techniques ( Protein and RNA extractions, qPCR, Western blot, Immunohistochemistry, Confocal ... microscopy, protein overexpression and gene silencing in mammalian cells, Isolation of primary liver cells and its culture, liver and intestinal organoids) as well… more