- Dana-Farber Cancer Institute (Boston, MA)
- …using containerized software in Docker is preferred. + Experience with a spatial- protein or spatial-transcript expression platform is a significant plus. + Familiar ... with the design and execution of the analysis of single-cell and bulk RNA-seq, ATAC-seq + Experiences with CyTOF, IHC, or mIF would be a significant plus. + Record of academic publications or contributions to open-source software Supervisory Responsibilities:… more
- System One (Andover, MA)
- …+ 4+6 years of experience + This role requires a strong understanding of protein biochemistry and a proven track record of applying a variety of analytical ... techniques, specifically N-glycan analysis, titer determination, Size Exclusion Chromatography (SEC), peptide mapping, imaged Capillary Isoelectric Focusing (iCE), and Capillary Gel Electrophoresis (CGE) along with some Mass Spectroscopy (MS) experience to… more
- Merck (Boston, MA)
- …hetero-bifunctional molecules (eg PROTACS, molecular glues, etc) and/ or targeted protein degradation considered a plus. **Education:** + PhD in biology, chemistry, ... biochemistry, chemical biology, pharmacology, biomedical sciences, pharmaceutical sciences or a related biological field with a minimum of 4 years post-Ph.D. experience [academia/industry] with publications; an MS degree with 8 years of industry experience; or… more
- J&J Family of Companies (Cambridge, MA)
- …analytical quantification of viral vector particles using relevant assessments including protein and PCR-based assays, particle potency testing via flow cytometry, ... and vector copy number (VCN) analysis. + Contribute to optimization efforts focused on increasing viral titers and purity to enhance the overall efficiency of production processes. + Support the development of innovative vector analytical and characterization… more
- Beth Israel Lahey Health (Boston, MA)
- …to the standards and in the quantities specified on the menu. Prepares protein salads, vegetables, fruits, sandwiches, etc. as needed. Finishes baking of frozen ... convenience food products. Works in the grill/pizza areas. 2. Works on the cash register in the cafeteria and ensures accuracy of drawer. 3. Plans and prioritizes catering deliveries. Organizes food and equipment for the function. Makes sandwiches, salads,… more
- Takeda Pharmaceuticals (Boston, MA)
- …AI/ML workflows that push the frontier of structure-based design across targeted protein degradation (TPD) and small molecules. The candidate will combine 3D ... generative modeling with physics-aware scoring, high-throughput automation, and rigorous benchmarking to improve hit finding, chemotype diversity, and lead optimization. . **_Accountabilities:_** + **Modeling & GenAI** + Train/finetune diffusion, transformer,… more
- ThermoFisher Scientific (Burlington, MA)
- …We need a scientist for our Purification Business to help with new protein purification products. **A Day in the Life:** + Develop new chromatographic purification ... solutions that meet customer specifications. + Implement statistical tools and design of experiments (DOE) to evaluate designs, optimize processes, and ensure new products meet quality attributes. + Perform analytical methods for surface characterization and… more
- Takeda Pharmaceuticals (Lexington, MA)
- …Kinetic Activity, Osmolality, Specific activity, Enzyme Activity, A280-320 protein concentration, pH, visual inspection and Reconstitution methodology. Provide ... subject matter expertise to junior level analyst in the lab. Proficiently use pH Meter, UV Spectrophotometer and solo VPE (Visual path extension), M5 and 384 Plate readers, 7500 fast Real-time PCR (Polymerase chain reaction) system and Osmometer. Provide… more
- Takeda Pharmaceuticals (Boston, MA)
- …suspensions, cryopreserve and recover cell lines and primary immune cells; execute protein and cell binding assays including ELISA and viral vector titration; ... perform flow cytometry-based experiments, including panel optimization, gating strategy, and data analysis; serve as an internal expert for BD Symphony and Aria Fusion flow cytometers, including maintenance and troubleshooting, consulting to optimize… more
- Bristol Myers Squibb (Cambridge, MA)
- …an expert in ADME and pharmaceutical drug development of small molecule drugs and protein therapeutics. In this role, you will represent the Dev DMPK function on ... cross-functional development project teams; oversee developmental drug metabolism and disposition, and non-clinical pharmacokinetics activities of multiple projects; be responsible for preparation of regulatory dossier / submissions; and assist in developing… more